Lee Sang Hyub, Seo Junghan, Jeong Dain, Hwang Jin Seop, Jang Jae-Won, Cho Yong Eun, Lee Dong-Geun, Park Choon Keun
Department of Neurosurgery, Spine Center, The Leon Wiltse Memorial Hospital, Suwon, Korea.
College of Nursing, University of Illinois Chicago, Chicago, IL, USA.
Neurospine. 2024 Sep;21(3):807-819. doi: 10.14245/ns.2448430.215. Epub 2024 Sep 30.
The unilateral biportal endoscopic posterior cervical foraminotomy (UBE-PCF) has been recently adopted for unilateral radiating arm pain due to cervical herniated intervertebral disc or foraminal stenosis. We systematically meta-analyzed clinical outcomes and complications of the UBE-PCF and compared them with those of full-endoscopic PCF (FE-PCF).
We systematically searched the PubMed, Embase, and Web of Science until February 29, 2024. Clinical outcomes and complications of the UBE-PCF and FE-PCF were collected and analyzed using the fixed-effect or random-effects model. Clinical outcomes of the UBE-PCF were compared with minimal clinically important difference (MCID) following PCF to evaluate the efficacy of UBE-PCF.
Ten studies were included in the meta-analysis. In the random-effects meta-analysis, the Neck Disability Index (NDI), visual analogue scale (VAS) neck, and VAS arm were significantly decreased after the UBE-PCF (p<0.001). The improvement of NDI, VAS neck, and VAS arm were significantly higher than MCID (p<0.05). The improvement of NDI, VAS neck, and VAS arm were not significantly different between the UBE-PCF and FE-PCF (p>0.05). Overall incidence of complications of the UBE-PCF was 6.2% (24 of 390). The most common complication was dura tear (2.1%, 8 of 390). The incidence in overall complications was not significantly different between the UBE-PCF and FE-PCF (p=0.813).
We found that the UBE-PCF significantly improved clinical outcomes. Regarding clinical outcomes and complications, the UBE-PCF and FE-PCF were not significantly different. Therefore, the UBE-PCF would be an advantageous surgical option comparable to FE-PCF for unilateral radiating arm pain.
单侧双通道内镜下颈椎后路椎间孔切开术(UBE-PCF)最近已被用于治疗因颈椎间盘突出或椎间孔狭窄引起的单侧放射性手臂疼痛。我们对UBE-PCF的临床疗效和并发症进行了系统的荟萃分析,并将其与全内镜下PCF(FE-PCF)的疗效和并发症进行比较。
我们系统检索了截至2024年2月29日的PubMed、Embase和Web of Science数据库。收集并使用固定效应或随机效应模型分析UBE-PCF和FE-PCF的临床疗效和并发症。将UBE-PCF的临床疗效与PCF术后的最小临床重要差异(MCID)进行比较,以评估UBE-PCF的疗效。
荟萃分析纳入了10项研究。在随机效应荟萃分析中,UBE-PCF术后颈部功能障碍指数(NDI)、颈部视觉模拟评分(VAS)和手臂VAS均显著降低(p<0.001)。NDI、颈部VAS和手臂VAS的改善均显著高于MCID(p<0.05)。UBE-PCF和FE-PCF在NDI、颈部VAS和手臂VAS的改善方面无显著差异(p>0.05)。UBE-PCF的总体并发症发生率为6.2%(390例中的24例)。最常见的并发症是硬脑膜撕裂(2.1%,390例中的8例)。UBE-PCF和FE-PCF在总体并发症发生率上无显著差异(p=0.813)。
我们发现UBE-PCF显著改善了临床疗效。在临床疗效和并发症方面,UBE-PCF和FE-PCF无显著差异。因此,对于单侧放射性手臂疼痛,UBE-PCF将是一种与FE-PCF相当的有利手术选择。