Wang Li-Qin, Wang Fei, Wang Xue-Hui
Department of First Clinical Medicine.
Department of Respiratory Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Medicine (Baltimore). 2020 Nov 6;99(45):e23077. doi: 10.1097/MD.0000000000023077.
Warm needling acupuncture (WNA) has been widely utilized for pain management in patients with diabetic peripheral neuropathy (DPN). However, its results are still inconsistent, and no systematic review has specifically addressed this issue. Thus, this systematic review will comprehensively and systematically investigate the effectiveness and safety of WNA for pain relief in DPN.
A comprehensive literature search of MEDLINE, EMBASE, Cochrane Library, Web of Science, Scopus, Allied and Complementary Medicine Database, CBM database, and China National Knowledge Infrastructure will be performed for randomized controlled trials that report WNA for pain relief in patients with DPN. All electronic databases will be searched from initial to the present without limitations of language and publication status. Two investigators will independently screen papers, collect data, and assess study quality. Cochrane risk of bias tool will be used for study quality assessment, and evidence quality will be evaluated using Grading of Recommendations Assessment, Development and Evaluations approach. RevMan 5.3 software will be applied for running statistical analysis.
This study will summarize the evidence for the effectiveness and safety of WNA for the management of pain in patients with DPN.
The findings of this study may provide helpful evidence to judge whether WNA for pain relief in DPN is effective or not.
温针疗法已被广泛用于糖尿病周围神经病变（DPN）患者的疼痛管理。然而，其结果仍不一致，且尚无专门针对此问题的系统评价。因此，本系统评价将全面、系统地研究温针疗法缓解DPN患者疼痛的有效性和安全性。
将对MEDLINE、EMBASE、Cochrane图书馆、科学网、Scopus、综合与补充医学数据库、中国生物医学文献数据库和中国知网进行全面的文献检索，以查找报告温针疗法缓解DPN患者疼痛的随机对照试验。所有电子数据库将从建库至当前进行检索，不受语言和出版状态的限制。两名研究人员将独立筛选文献、收集数据并评估研究质量。将使用Cochrane偏倚风险工具进行研究质量评估，并采用推荐分级的评估、制定与评价方法评估证据质量。将应用RevMan 5.3软件进行统计分析。
本研究将总结温针疗法治疗DPN患者疼痛有效性和安全性的证据。
本研究结果可能为判断温针疗法缓解DPN患者疼痛是否有效提供有用的证据。
