Child and Adolescent Psychiatry Unit, Necker Enfant Malades Hospital, Paris, France.
Savoie Mont Blanc University of Annecy-le-Vieux, Research Institute of Management and Economics, IREGE, Annecy-le-Vieux, Auvergne-Rhône-Alpes, France.
Epilepsy Behav. 2020 Dec;113:107401. doi: 10.1016/j.yebeh.2020.107401. Epub 2020 Nov 5.
The aim of this study was to investigate attachment behavior in a population of infants with infantile spasms (ISs) using the Strange Situation Procedure (SSP) and to explore factors associated with the infants' attachment behavior.
The SSP was assessed in a population of 29 children with ISs during the second year of life. In mothers, we assessed anxiety, depression, maternal emotions, and perception of the temperament of the child, and sociodemographic characteristics. In children, we assessed epilepsy characteristics, response to antiepileptic drugs (AEDs) at the time of the SSP, and the child's outcome at 3 years of age, in terms of intellectual disability (ID), and autism spectrum disorder (ASD).
Insecure attachment was higher than in the general population (68% versus 32%). It was associated with maternal anxiety, sadness, and maternal representation of the child at 12 months but with none of the child characteristics including ID, ASD, response to AEDs, or ISs etiology.
Nonspecific dimensions were more important than disease characteristics for the infants' attachment behavior. In conclusion, we propose that interventions targeting mother-child interaction could prevent attachment insecurity and the developmental consequences of early epilepsy.
本研究旨在通过陌生情境程序（SSP）调查婴儿痉挛症（IS）患儿群体的依恋行为，并探讨与婴儿依恋行为相关的因素。
在 29 名 IS 患儿生命的第二年进行 SSP 评估。在母亲中，我们评估了焦虑、抑郁、母亲情绪以及对儿童气质的感知和社会人口特征。在儿童中，我们评估了癫痫特征、SSP 时抗癫痫药物（AED）的反应以及儿童在 3 岁时的智力障碍（ID）和自闭症谱系障碍（ASD）的结局。
不安全依恋的比例高于一般人群（68%比 32%）。它与母亲在 12 个月时的焦虑、悲伤和对孩子的代表性有关，但与儿童的任何特征无关，包括 ID、ASD、对 AED 的反应或 IS 的病因。
非特异性维度比疾病特征对婴儿的依恋行为更重要。总之，我们提出针对母婴互动的干预措施可能预防早期癫痫的依恋障碍和发育后果。
