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自闭症的多因素模型与因果关系问题。

The polyfactorial model of autism and the question of causality.

作者信息

Golse Bernard

机构信息

Université Paris Cité, Paris, France.

出版信息

Front Psychiatry. 2023 Jun 27;14:1117807. doi: 10.3389/fpsyt.2023.1117807. eCollection 2023.

DOI:10.3389/fpsyt.2023.1117807
PMID:37441148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10333481/
Abstract

After recalling the different pediatric, psychopathological and child psychiatric models of mental disorders in children and adolescents, the author presents in detail the so-called polyfactorial model, which includes primary, secondary, and mixed factors. This model is the epistemological heir of the Freudian concept of "complementary series." The example of autism is then explored as a paradigm of the usefulness of this polyfactorial model. Finally, we reflect on the notion of causality, from Aristotelian causality to epigenetic causality, which could 1 day re-legitimize psychoanalysis and the impact of the relationship on genome expression.

摘要

在回顾了儿童和青少年精神障碍的不同儿科、精神病理学和儿童精神病学模型后,作者详细介绍了所谓的多因素模型,该模型包括主要因素、次要因素和混合因素。这个模型是弗洛伊德“互补系列”概念的认识论继承者。然后以自闭症为例,探讨了这种多因素模型的实用性。最后,我们思考了因果关系的概念,从亚里士多德的因果关系到表观遗传因果关系,这可能有一天会重新使精神分析合法化以及关系对基因组表达的影响。

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The polyfactorial model of autism and the question of causality.自闭症的多因素模型与因果关系问题。
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本文引用的文献

1
Attachment insecurity in infants with infantile spasms: Maternal anxiety and sadness, and infant's temperament outweigh disease severity.婴儿痉挛症婴儿的依恋不安全感:母亲的焦虑和悲伤,以及婴儿的气质比疾病严重程度更重要。
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Linking neuroscience and psychoanalysis from a developmental perspective: why and how?从发展的视角看神经科学与精神分析的联系:为何以及如何联系?
J Physiol Paris. 2010 Dec;104(6):303-8. doi: 10.1016/j.jphysparis.2010.09.005. Epub 2010 Oct 1.
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Bull Acad Natl Med. 2009 Feb;193(2):299-304; discussion 304-5.
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Gene-environment interactions in the development of complex disease phenotypes.复杂疾病表型发展中的基因-环境相互作用。
Int J Environ Res Public Health. 2008 Mar;5(1):4-11. doi: 10.3390/ijerph5010004.
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Autism and social movements: French parents' associations and international autistic individuals' organisations.自闭症与社会运动:法国家长协会及国际自闭症患者组织
Sociol Health Illn. 2008 Jan;30(1):76-96. doi: 10.1111/j.1467-9566.2007.01053.x.
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