Engineering Research Center of Knitting Technology, Ministry of Education, College of Textile Science and Engineering, Jiangnan University, Wuxi, 214122, China.
Engineering Research Center of Knitting Technology, Ministry of Education, College of Textile Science and Engineering, Jiangnan University, Wuxi, 214122, China; Key Laboratory of Clean Dyeing and Finishing Technology of Zhejiang Province, Shaoxing University, Shaoxing, 3212000, China.
J Mech Behav Biomed Mater. 2021 Feb;114:104192. doi: 10.1016/j.jmbbm.2020.104192. Epub 2020 Nov 4.
In this paper, two most representative hernia repair meshes were prepared with 0.15 mm polypropylene monofilaments via warp knitting technology, and their mechanical properties were tested in various aspects. Meanwhile, a focused investigation of the boundary conditions between the sutures and the mesh was simulated in several directions innovatively. The results revealed that the hernia repair mesh with different structures has different mechanical properties, and the mechanical properties of standard hernia repair mesh were superior to that of lightweight hernia repair mesh. In order to reduce foreign body sensation and postoperative adverse reactions significantly, the lightweight hernia repair mesh may be preferred. At the same time, the mesh should be placed in the proper direction to comply with the anisotropy of abdominal wall during operation. The area where the hernia mesh is in contact with the sutures was vulnerable to damage. The curved or wrinkled area of the hernia repair mesh increases with the increase of load, which may lead to poor tissue growth, a strong inflammatory response, and even the recurrence of the hernia. Therefore, the hernia repair meshes with different structures may require unique suture techniques. And they also should be further treated prior to implantation. This study provides a theoretical basis for development, utilization and improvement of meshes. Further research will focus on the biomechanical properties of the mesh after implantation in vivo studies.
本文采用经编工艺制备了两种最具代表性的疝修补网片,分别由 0.15mm 聚丙烯单丝编织而成,并从多方面测试了它们的力学性能。同时,还创新性地从几个方向对缝线与网片交界处的边界条件进行了深入研究。结果表明,不同结构的疝修补网片具有不同的力学性能,标准疝修补网片的力学性能优于轻质疝修补网片。为了显著降低异物感和术后不良反应,可能更倾向于使用轻质疝修补网片。同时,网片应按手术时腹壁的各向异性正确放置。疝修补网片与缝线接触的区域容易受损。疝修补网片的弯曲或起皱区域随着负荷的增加而增加,这可能导致组织生长不良、强烈的炎症反应,甚至疝的复发。因此,不同结构的疝修补网片可能需要独特的缝线技术。并且在植入前还需要进一步处理。本研究为网片的开发、利用和改进提供了理论依据。进一步的研究将集中在体内研究中植入后的网片生物力学性能上。