Katayama Yoshio
Hematology, Kobe University Hospital.
Rinsho Ketsueki. 2020;61(9):1058-1063. doi: 10.11406/rinketsu.61.1058.
Mammals have developed bone marrow (BM) inside the bone tissue because of evolution. Now, it appears that bone tissue displays functional communication with the hematopoietic system. Osteoblast lineage cells serve as a part of the microenvironment for immature hematopoietic cells, whereas mature hematopoietic cells play important roles in regulating osteoblast activity. The nervous system maintains the balance between the hematopoietic and skeletal systems. An understanding of the multiple-organ network that exists between the BM and other systems is useful to elucidate phenomena in clinical hematology and even in other fields, an area which I propose to call "marrowlogy."
由于进化，哺乳动物在骨组织内形成了骨髓（BM）。现在看来，骨组织与造血系统之间存在功能联系。成骨细胞系细胞是未成熟造血细胞微环境的一部分，而成熟造血细胞在调节成骨细胞活性方面发挥着重要作用。神经系统维持着造血系统和骨骼系统之间的平衡。了解骨髓与其他系统之间存在的多器官网络，有助于阐明临床血液学甚至其他领域的现象，我提议将这一领域称为“骨髓学”。
