Rosinsky Philip J, Chen Jeffery W, Yelton Mitchell J, Lall Ajay C, Maldonado David R, Meghpara Mitchell B, Shapira Jacob, Domb Benjamin G
American Hip Institute Research Foundation, 999 E Touhy Ave, Suite 450, Des Plaines, IL 60018, USA.
Vanderbilt University School of Medicine, 1161 21st Ave, Nashville, TN 37232, USA.
J Hip Preserv Surg. 2020 Apr 14;7(2):272-280. doi: 10.1093/jhps/hnaa015. eCollection 2020 Jul.
The purpose of this study was to determine (i) if failing to achieve a patient-reported outcome (PRO) threshold at 1 year was associated with secondary operations at minimum 2-year follow-up and (ii)what outcome measure and threshold has the highest association with future surgeries. Inclusion criteria for this study were cases of primary hip arthroscopy between July 2014 and April 2017. Included patients had recorded pre-operative and 1-year post-operative modified Harris Hip Score (mHHS) and 12-item international Hip Outcome Tool (iHOT-12) scores. Patients were classified based on their ability to achieve minimal clinical important difference (MCID), substantial clinical benefit (SCB) and patient acceptable symptom state (PASS) for each PRO and the status of secondary operations at minimum 2-year follow-up. The sensitivity, specificity, accuracy, positive likelihood ratio and negative likelihood ratio for these thresholds were calculated. Of 425 eligible cases, 369 (86.8%) had minimum 2-year follow-up. Of the included patients, 28 underwent secondary operations (7.59%), with 14 undergoing secondary arthroscopies (3.79%) and 14 converting to total hip arthroplasty (3.79%). For mHHS, 267 (72.4%), 173 (46.9%) and 277 (75.1%) hips met MCID, SCB and PASS, respectively. For iHOT-12, 234 (63.4%), 218 (59.1%) and 280 (75.9%) hips met the respective thresholds. The highest specificity, sensitivity and accuracy were identified as for iHOT-12 MCID (0.79), iHOT-12 PASS (0.79) and iHOT-12 MCID (0.77), respectively. Patients not attaining MCID and PASS for mHHS and iHOT-12 at 1-year post-operatively are at increased risk of secondary operation. The most accurate threshold associated with secondary operation (0.77) is not achieving iHOT-12 MCID. Level of evidence: retrospective case series: level IV.
(i)在1年时未达到患者报告结局(PRO)阈值是否与至少2年随访期内的二次手术相关;(ii)何种结局指标和阈值与未来手术的关联度最高。本研究的纳入标准为2014年7月至2017年4月期间的初次髋关节镜检查病例。纳入患者记录了术前和术后1年的改良Harris髋关节评分(mHHS)以及12项国际髋关节结局工具(iHOT-12)评分。根据患者在每种PRO方面达到最小临床重要差异(MCID)、显著临床获益(SCB)和患者可接受症状状态(PASS)的能力以及至少2年随访期内的二次手术状态进行分类。计算这些阈值的敏感性、特异性、准确性、阳性似然比和阴性似然比。在425例符合条件的病例中,369例(86.8%)进行了至少2年的随访。在纳入患者中,28例(7.59%)接受了二次手术,其中14例(3.79%)接受了二次关节镜检查,14例(3.79%)转为全髋关节置换术。对于mHHS,分别有267例(72.4%)、173例(46.9%)和277例(75.1%)髋关节达到MCID、SCB和PASS。对于iHOT-12,分别有234例(63.4%)、218例(59.1%)和280例(75.9%)髋关节达到各自阈值。最高的特异性、敏感性和准确性分别确定为iHOT-12 MCID(0.79)、iHOT-12 PASS(0.79)和iHOT-12 MCID(0.77)。术后1年时mHHS和iHOT-12未达到MCID和PASS的患者二次手术风险增加。与二次手术相关的最准确阈值(0.77)是未达到iHOT-12 MCID。证据水平:回顾性病例系列:IV级。