Ueland Thomas E, Disantis Ashley, Carreira Dominic S, Martin RobRoy L
Peachtree Orthopedics, Atlanta, Georgia.
Department of Physical Therapy, Duquesne University, Pittsburgh, Pennsylvania.
JBJS Rev. 2021 Jan 26;9(1):e20.00084. doi: 10.2106/JBJS.RVW.20.00084.
Defining success in hip arthroscopy through patient-reported outcome measures (PROMs) is complicated by the wide range of available questionnaires and overwhelming amount of information on how to interpret scores. The minimal clinically important difference (MCID), patient acceptable symptom state (PASS), and substantial clinical benefit (SCB) are collectively known as clinically important outcome values (CIOVs). These CIOVs provide benchmarks for meaningful improvement. The aims of this review were to update the evidence regarding joint-specific PROMs used for hip arthroscopy and to collate available CIOVs in this population.
A systematic review of MEDLINE and Embase databases was performed to identify studies reporting measurement properties of PROMs utilized for hip arthroscopy. Metrics of reliability, validity, and responsiveness were extracted and graded according to an international Delphi study. Questionnaire interpretability was evaluated through CIOVs.
Twenty-six studies were reviewed. One study validated a novel questionnaire, 3 studies validated existing questionnaires, and 22 studies reported CIOVs. The most evidence supporting interpretability was found for the Hip Outcome Score (HOS, 11 studies), modified Harris hip score (mHHS, 10 studies), and International Hip Outcome Tool-12 (iHOT-12, 9 studies). Scores indicative of the smallest perceptible versus substantial clinically relevant changes were reported for the iHOT-12 (12 to 15 versus 22 to 28), iHOT-33 (10 to 12 versus 25 to 26), HOS-Activities of Daily Living (HOS-ADL, 9 to 10 versus 10 to 16), HOS-Sports (14 to 15 versus 25 to 30), and mHHS (7 to 13 versus 20 to 23). Absolute postoperative scores indicative of an unsatisfactory versus a desirable outcome were reported for the iHOT-12 (below 56 to 63 versus above 86 to 88), iHOT-33 (below 58 versus above 64 to 82), HOS-ADL (below 87 to 92 versus above 94), HOS-Sports (below 72 to 80 versus above 78 to 86), and mHHS (below 74 to 85 versus above 83 to 95).
Six questionnaires had reported clinically important outcome thresholds, with the HOS, mHHS, and iHOT-12 having the most information to support score interpretation. Thresholds for the HOS, mHHS, iHOT-12, and iHOT-33 describe desirable absolute PROM scores and minimum and substantial change scores within 5 years following hip arthroscopy. Despite substantial heterogeneity in calculation methodology, included cohorts, and follow-up time, available interpretability values could be meaningfully summarized.
In light of increasing use of PROMs in orthopaedics, a summary of the available CIOVs provides guidance for clinicians in mapping numerical scores from PROMs onto clinical benchmarks.
通过患者报告的结局指标(PROMs)来定义髋关节镜手术的成功存在复杂性,这是因为可用的调查问卷种类繁多,且关于如何解读分数的信息量巨大。最小临床重要差异(MCID)、患者可接受症状状态(PASS)和显著临床获益(SCB)统称为临床重要结局值(CIOVs)。这些CIOVs为有意义的改善提供了基准。本综述的目的是更新有关用于髋关节镜手术的关节特异性PROMs的证据,并整理该人群中可用的CIOVs。
对MEDLINE和Embase数据库进行系统综述,以识别报告用于髋关节镜手术的PROMs测量属性的研究。根据一项国际德尔菲研究提取并分级可靠性、有效性和反应性指标。通过CIOVs评估问卷的可解释性。
共审查了26项研究。1项研究验证了一种新型问卷,3项研究验证了现有问卷,22项研究报告了CIOVs。支持可解释性的证据最多的是髋关节结局评分(HOS,11项研究)、改良Harris髋关节评分(mHHS,10项研究)和国际髋关节结局工具-12(iHOT-12,9项研究)。报告了iHOT-12(12至15分与22至28分)、iHOT-33(10至12分与25至26分)、HOS-日常生活活动(HOS-ADL,9至10分与10至16分)、HOS-运动(14至15分与25至30分)和mHHS(7至13分与20至23分)中指示最小可察觉与显著临床相关变化的分数。报告了iHOT-12(低于56至63分与高于86至88分)、iHOT-33(低于58分与高于64至82分)、HOS-ADL(低于87至92分与高于94分)、HOS-运动(低于72至80分与高于78至86分)和mHHS(低于74至85分与高于83至95分)中指示不满意与满意结局的术后绝对分数。
六项问卷报告了临床重要结局阈值,其中HOS、mHHS和iHOT-12有最多信息支持分数解读。HOS、mHHS、iHOT-12和iHOT-33的阈值描述了髋关节镜手术后5年内理想的绝对PROM分数以及最小和显著变化分数。尽管在计算方法、纳入队列和随访时间方面存在很大异质性,但可用的可解释性值仍可进行有意义的总结。
鉴于PROMs在骨科中的使用日益增加,可用CIOVs的总结为临床医生将PROMs的数字分数映射到临床基准提供了指导。