Gurbuz Begum Calim, Inceman Hande Nur, Aydemir Merve, Celtik Coskun, Gerenli Nelgin, Zemheri Ebru
Department of Pathology, Istanbul Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Department of Pediatric Gastroenterology, Istanbul Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
North Clin Istanb. 2020 Aug 17;7(5):499-505. doi: 10.14744/nci.2020.70037. eCollection 2020.
() is a gram-negative bacterium and one of the reasons for gastritis, peptic and duodenal ulcers. It is a crucial public health problem for both children and adults, especially in developing countries. This study aims to investigate the prevalence of positivity in children and to compare with updated Sydney classification criteria.
This study was conducted from January 2015 to June 2017. This study included 885 children aged 0-17 year(s). Endoscopic biopsies were evaluated for the diagnosis of infection due to .
The findings showed that 418 (47.2%) of 885 children were positive for , and this positivity had a significantly increasing correlation with the presence of chronic inflammation, neutrophilic activity, lymphoid aggregates, and follicles. Erythematous pangastritis and antral nodularity on endoscopic findings had a correlation with positivity.
In this hospital-based study, the findings suggest that infection is a problem for children and more extensive studies are needed to determine the prevalence of positivity among children.
（某种细菌名称）是一种革兰氏阴性菌，是胃炎、消化性溃疡和十二指肠溃疡的病因之一。对儿童和成人来说，尤其是在发展中国家，它都是一个至关重要的公共卫生问题。本研究旨在调查儿童中该菌阳性的患病率，并与更新后的悉尼分类标准进行比较。
本研究于2015年1月至2017年6月进行。该研究纳入了885名0至17岁的儿童。对内镜活检组织进行评估以诊断该菌感染情况。
结果显示，885名儿童中有418名（47.2%）该菌呈阳性，且这种阳性与慢性炎症、中性粒细胞活性、淋巴样聚集物和滤泡的存在呈显著正相关。内镜检查发现的红斑性全胃炎和胃窦结节与该菌阳性相关。
在这项基于医院的研究中，研究结果表明该菌感染对儿童来说是个问题，需要开展更广泛的研究以确定儿童中该菌阳性的患病率。
