Yao Liu, Li-Min Liu, Yuan-Gen Xiong, Xue-Bin Shen, Huan Liu, Si-Hui Nian
School of Pharmacy, Wannan Medical College Wuhu 241002, China.
Anhui College of Traditional Chinese Medicine Wuhu 241002, China.
Zhongguo Zhong Yao Za Zhi. 2020 Sep;45(18):4349-4357. doi: 10.19540/j.cnki.cjcmm.20200604.601.
The plants of genus Clinopodium are perennial herbs of Labiatae, which are widely distributed in the world and have a promising medicinal value. Modern researches have shown flavonoids, triterpenoid saponins, terpene glycosides, terpenoids, volatile oils and phenylpropanoids are the main compounds in the plants, presenting various pharmacological effects such as hemostasis, anti-bacteria, anti-inflammation, immunoregulation, reducing blood glucose, antioxidation, and anti-tumor effects. The preparations made of those plants are mainly used for treatment of various bleeding diseases in clinical application. In this review, we systematically summarized the research progress on taxonomy, resource distribution, chemical compositions, pharmacological activities, and clinical application of the medicinal plants of genus Clinopodium. This review provides references and scientific basis for further research and development of genus Clinopodium.
风轮菜属植物为唇形科多年生草本植物,广泛分布于世界各地,具有良好的药用价值。现代研究表明,黄酮类、三萜皂苷类、萜烯糖苷类、萜类、挥发油类和苯丙素类是该属植物中的主要化合物,具有止血、抗菌、抗炎、免疫调节、降血糖、抗氧化和抗肿瘤等多种药理作用。这些植物制成的制剂在临床应用中主要用于治疗各种出血性疾病。在本综述中,我们系统总结了风轮菜属药用植物在分类学、资源分布、化学成分、药理活性及临床应用方面的研究进展。本综述为风轮菜属植物的进一步研发提供了参考和科学依据。