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使用免费软件和桌面打印机创建的三维先天性心脏模型:准确性评估、技术方面和临床应用。

Three-Dimensional Congenital Heart Models Created With Free Software and a Desktop Printer: Assessment of Accuracy, Technical Aspects, and Clinical Use.

机构信息

21785UCLA Mattel Children's Hospital, Children's Heart Center, Los Angeles, CA, USA.

Diagnostic Cardiovascular Imaging Laboratory, Department of Radiology, 12222David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

出版信息

World J Pediatr Congenit Heart Surg. 2020 Nov;11(6):797-801. doi: 10.1177/2150135120952072.

Abstract

BACKGROUND

Three-dimensional printing is increasingly recognized as a valuable tool for congenital heart disease (CHD) procedural planning and education. Cost and complexity currently limit the more widespread adoption of this technology. We sought to demonstrate the accuracy of 3D printed CHD models created from contrast-enhanced magnetic resonance imaging (MRI) and computed tomography (CT) scans using free software and an inexpensive desktop fused filament fabrication (FFF) printer.

METHODS

Solid segmentations of the intracardiac blood pool were created with the program ITK-SNAP. Using the computer program Meshmixer, the segmentation model was hollowed to create a 0.8 mm shell with the inner surface representing endocardium. Three-dimensional models were created on an FFF printer. Four arteries and a ventricular septal defect (VSD) were 3D printed and measured for accuracy. Five models were used to assess candidacy for biventricular surgical repair and one to guide an interventional catheterization.

RESULTS

All six patients underwent intervention planned with the 3D models. The computer model shell walls all achieved specifications within 0.05 mm of the designated 0.8 mm thickness and the original solid blood pool segmentation fit within the hollowed 3D model. The 3D printed arteries and VSD all measured accurately to within 0.5 mm of their source computer model.

CONCLUSION

Accurate 3D printed models of complex, pediatric CHD may be created from volumetric MRI and CT studies using free online software and printed on an inexpensive desktop printer.

摘要

背景

三维打印技术越来越被认为是先天性心脏病(CHD)手术规划和教育的有价值工具。成本和复杂性目前限制了这项技术的更广泛应用。我们旨在展示使用免费软件和廉价的桌面熔丝制造(FFF)打印机从对比增强磁共振成像(MRI)和计算机断层扫描(CT)扫描创建的 3D 打印 CHD 模型的准确性。

方法

使用 ITK-SNAP 程序创建心内血池的实体分割。使用计算机程序 Meshmixer,将分割模型掏空以创建具有 0.8mm 壁厚的 0.8mm 壳,内表面代表心内膜。在 FFF 打印机上创建三维模型。打印三个动脉和一个室间隔缺损(VSD)以测量准确性。使用五个模型评估双心室手术修复的适应证,使用一个模型指导介入导管插入术。

结果

所有六名患者均接受了计划用 3D 模型进行的干预。计算机模型壳壁均达到了指定的 0.8mm 厚度的 0.05mm 以内的规格,并且原始实心血池分割符合空心 3D 模型。打印的动脉和 VSD 均能准确测量到与其原始计算机模型的 0.5mm 以内。

结论

使用免费在线软件从容积 MRI 和 CT 研究中可以创建复杂的儿科 CHD 的精确 3D 打印模型,并使用廉价的桌面打印机打印。

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