三维打印模型在先天性心脏病解剖中的准确性定量评估。
Quantitative Assessment of 3D Printed Model Accuracy in Delineating Congenital Heart Disease.
机构信息
Discipline of Medical Radiation Science, Curtin Medical School, Curtin University, GPO Box, U1987, Perth, WA 6845, Australia.
Discipline of Exploration Geophysics, Western Australian School of Mines, Minerals, Energy and Chemical Engineering, Curtin University, Perth, WA 6845, Australia.
出版信息
Biomolecules. 2021 Feb 12;11(2):270. doi: 10.3390/biom11020270.
BACKGROUND
Three-dimensional (3D) printing is promising in medical applications, especially presurgical planning and the simulation of congenital heart disease (CHD). Thus, it is clinically important to generate highly accurate 3D-printed models in replicating cardiac anatomy and defects. The present study aimed to investigate the accuracy of the 3D-printed CHD model by comparing them with computed tomography (CT) images and standard tessellation language (STL) files.
METHODS
Three models were printed, comprising different CHD pathologies, including the tetralogy of Fallot (ToF), ventricular septal defect (VSD) and double-outlet right-ventricle (DORV). The ten anatomical locations were measured in each comparison. Pearson's correlation coefficient, Bland-Altman analysis and intra-class correlation coefficient (ICC) determined the model accuracy.
RESULTS
All measurements with three printed models showed a strong correlation (r = 0.99) and excellent reliability (ICC = 0.97) when compared to original CT images, CT images of the 3D-printed models, STL files and 3D-printed CHD models.
CONCLUSION
This study demonstrated the high accuracy of 3D-printed heart models with excellent correlation and reliability when compared to multiple source data. Further investigation into 3D printing in CHD should focus on the clinical value and the benefits to patients.
背景
三维（3D）打印在医学应用中具有广阔的前景，特别是在术前规划和先天性心脏病（CHD）模拟方面。因此，生成能够高度准确复制心脏解剖结构和缺陷的 3D 打印模型具有重要的临床意义。本研究旨在通过比较 CT 图像和标准网格语言（STL）文件，来评估 3D 打印 CHD 模型的准确性。
方法
打印了三个模型，包括不同的 CHD 病理，包括法洛四联症（ToF）、室间隔缺损（VSD）和双出口右心室（DORV）。在每种比较中测量了十个解剖位置。Pearson 相关系数、Bland-Altman 分析和组内相关系数（ICC）确定了模型的准确性。
结果
与原始 CT 图像、3D 打印模型的 CT 图像、STL 文件和 3D 打印 CHD 模型相比，三种打印模型的所有测量值均表现出很强的相关性（r = 0.99）和极好的可靠性（ICC = 0.97）。
结论
本研究表明，3D 打印心脏模型具有很高的准确性，与多种来源的数据相关性好，可靠性高。进一步研究 CHD 中的 3D 打印应关注其临床价值和对患者的益处。
Zotero 插件