Department of Immunology, School of Medicine, Kyungpook National University, Daegu, Korea.
Dana Plastic Surgery Clinic, Seoul, Korea.
Dermatol Surg. 2021 May 1;47(5):e191-e194. doi: 10.1097/DSS.0000000000002878.
Various types of follicular trauma occur during follicular unit excision (FUE). However, the effects of different types of follicular injury on graft survival have not been reported.
This study was performed to evaluate the differences in hair follicle survival by the type of follicular injury, including paring, fracture, and bulb injury.
Seven healthy patients who underwent hair transplant surgery by FUE were enrolled in the study. For each patient, 10 single-hair follicular unit grafts per injury group (paring, fracture, bulb injury, or intact) were differentiated. Using sharp implanters, 10 grafts of each of the 4 injury types were transplanted into mice, and the mice were sacrificed 5 months after transplantation. The skin was excised at each of the 4 locations, and newly formed follicular units were counted and photographed under a microscope.
Of 70 hair follicles in each group, the number of successfully engrafted follicles was 50 (71.43%) in the intact group, 36 (51.43%) in the paring injury group, 9 (12.86%) in the fracture injury group, and 31 (44.29%) in the bulb injury group.
Grafts with minor injury had a lower survival rate than intact grafts. Fractured follicles showed the lowest survival rate.
毛囊单位提取术（FUE）过程中会发生各种类型的毛囊损伤。然而，不同类型的毛囊损伤对移植体存活率的影响尚未见报道。
本研究旨在评估不同类型的毛囊损伤（削切、断裂和球部损伤）对毛囊存活率的影响。
本研究纳入了 7 例行 FUE 毛发移植术的健康患者。每位患者均按损伤类型（削切、断裂、球部损伤或完整）区分出 10 个单毛囊单位移植体。使用锋利的植入器，将 4 种损伤类型中的每种各 10 个移植体移植到小鼠体内，移植后 5 个月处死小鼠。在 4 个部位分别切取皮肤，在显微镜下计数和拍摄新形成的毛囊单位。
每组 70 个毛囊中，完整组的成功植入毛囊数为 50 个（71.43%），削切损伤组为 36 个（51.43%），断裂损伤组为 9 个（12.86%），球部损伤组为 31 个（44.29%）。
损伤较小的移植体存活率低于完整移植体。断裂的毛囊存活率最低。
