Department of Dermatology, University of California, Irvine, Irvine, California.
AboutSkin Dermatology and DermSurgery, Greenwood Village, Colorado.
Dermatol Surg. 2020 Dec;46(12):1676-1682. doi: 10.1097/DSS.0000000000002757.
Laser procedures are becoming more prevalent across multiple medical specialties for a variety of indications. The plumes created by these lasers have raised concern for the dissemination of an infectious material.
To review and summarize the information on viral dissemination in laser plumes available in the literature.
Data Sources A systematic review was performed on English and non-English articles using the PubMed and the Cochrane databases. A manual search of bibliographies from relevant articles was also performed to collect additional studies.
Only articles in the English language with full texts available that pertained to viral particles in laser plumes were included. Data Extraction Two authors performed independent article selections using predefined inclusion and exclusion criteria.
There have been case reports of possible transmission of human papillomavirus (HPV) by inhalation of laser-produced aerosols. Multiple investigators have attempted to recreate this scenario in the laboratory to qualify this risk. Others have conducted clinical experiments to determine the presence of HPV in laser plumes.
The current body of the literature suggests that laser surgeons are at a risk for HPV exposure by inhalation of laser-derived aerosols. We offer best practice recommendations for laser operators.
激光技术在多个医学专业中得到了广泛应用，适用于多种适应证。这些激光产生的烟雾引起了人们对传染性物质传播的关注。
回顾和总结激光烟雾中病毒传播的相关文献信息。
资料来源 对 PubMed 和 Cochrane 数据库中的英文和非英文文章进行了系统综述。还对相关文章的参考文献进行了手工搜索，以收集其他研究。
仅纳入与激光烟雾中的病毒颗粒相关、可获取全文的英文文章。数据提取 两位作者使用预设的纳入和排除标准进行了独立的文章选择。
有病例报告称，吸入激光产生的气溶胶可能会传播人乳头瘤病毒（HPV）。许多研究人员试图在实验室重现这种情况以确定这种风险。其他人进行了临床实验以确定激光烟雾中是否存在 HPV。
目前的文献资料表明，激光外科医生可能因吸入激光衍生的气溶胶而接触 HPV。我们为激光操作人员提供了最佳的实践建议。
