Nam Kyung-Hwa, Park Sang-Woo, Yun Seok-Kweon
Department of Dermatology, Presbyterian Medical Center, Jeonju, South Korea.
Department of Dermatology, Chonbuk National University Medical School, Jeonju, South Korea.
Indian J Dermatol. 2020 Sep-Oct;65(5):401-405. doi: 10.4103/ijd.IJD_366_18.
Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare.
This study was undertaken to examine the clinicohistopathological features of CFH of the finger.
This is a retrospective study of 12 CFHs located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files.
Ages of the CHF of the finger affected individuals ranged from 9 to 48 years with a male-to-female ratio of 1.4:1. Picker's nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of CFH ventured. Fibrocollagenous type was the most common histological type. Majority of the cases were mitotically inactive, exhibiting only 0-1 mitoses per high-power field and there was no recurrence. Tumor cells were uniformly CD34 negative.
Because CFH can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of CFH of the finger may lead to more aggressive treatment. Dermatologists should include CFH in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management.
皮肤纤维组织细胞瘤（CFH）是一种常见的良性皮肤肿瘤，主要发生于四肢或躯干。然而，手指部的CFH较为罕见。
本研究旨在探讨手指部CFH的临床组织病理学特征。
这是一项对韩国一家三级医院12例手指部CFH的回顾性研究。所有病例切片均从存档文件中调取。
手指部CFH患者年龄9至48岁，男女比例为1.4:1。最常见的临床诊断为皮克氏结节或疣。12例中仅2例在活检前诊断为CFH。纤维胶原型是最常见的组织学类型。大多数病例有丝分裂不活跃，每高倍视野仅见0 - 1个有丝分裂象，且无复发。肿瘤细胞均为CD34阴性。
由于CFH可能类似包括隆突性皮肤纤维肉瘤在内的恶性肿瘤，对手指部CFH的发生缺乏认识可能导致更积极的治疗。皮肤科医生在对手指部局限性结节进行鉴别诊断时应考虑CFH，以确保恰当处理。
