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过敏性肺炎、变应性支气管肺曲霉病和其他嗜酸性粒细胞性肺病。

Hypersensitivity pneumonitis, allergic bronchopulmonary aspergillosis and other eosinophilic lung diseases.

机构信息

Division of Pulmonary, Critical Care & Sleep Medicine, University of California San Diego, La Jolla, CA, United States.

Division of Pulmonary, Critical Care & Sleep Medicine, University of California San Diego, La Jolla, CA, United States.

出版信息

Curr Opin Immunol. 2020 Oct;66:129-135. doi: 10.1016/j.coi.2020.10.005. Epub 2020 Nov 6.

Abstract

Hypersensitivity pneumonitis (HP) is traditionally classified into acute, subacute and chronic forms. A high index of suspicion and a detailed investigation into the patient's environment is the key to diagnosis and treatment of HP. Eosinophilic lung diseases can be broadly categorized as idiopathic (acute eosinophilic pneumonia, chronic eosinophilic pneumonia, eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndromes), those with known cause (allergic bronchopulmonary aspergillosis, drugs, parasitic and non-parasitic infections), and those associated with other known lung diseases (asthma, interstitial lung diseases and lung cancers). A detailed review of drug intake, toxin exposures, and travel history is essential in the differential diagnosis of eosinophilic lung diseases.

摘要

过敏性肺炎(HP)传统上分为急性、亚急性和慢性。对患者环境进行高度怀疑和详细调查是诊断和治疗 HP 的关键。嗜酸性肺病可大致分为特发性(急性嗜酸性肺炎、慢性嗜酸性肺炎、嗜酸性肉芽肿伴多血管炎和高嗜酸性粒细胞综合征)、已知原因(变应性支气管肺曲霉病、药物、寄生虫和非寄生虫感染)和与其他已知肺病相关(哮喘、间质性肺疾病和肺癌)。在嗜酸性肺病的鉴别诊断中,详细审查药物摄入、毒素暴露和旅行史是必不可少的。

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