AlShaheen Hamad, Abuzied Yacoub, Aldalbahi Hosam, AlSheef Mohammed
Infectious Disease and Internal Medicine, Medical Specialties Department, King Fahad Medical City, Riyadh, SAU.
Nursing Department, Rehabilitation Hospital, King Fahad Medical City, Riyadh, SAU.
Cureus. 2023 Jun 21;15(6):e40727. doi: 10.7759/cureus.40727. eCollection 2023 Jun.
Aspergillosis is a serious pathologic condition caused by that commonly affects immunocompromised patients. In recent years, it has been demonstrated that infection can cause a wide spectrum of pulmonary diseases, including allergic bronchopulmonary aspergillosis, chronic necrotizing aspergillosis, aspergilloma, and invasive aspergillosis. The characteristic computed tomography (CT) and pathologic findings of the various pulmonary manifestations of infection are illustrated and reviewed in this case report. is an infrequent infection that affects the lungs in severely immunosuppressed patients. In this paper, we report the case of a 50-year-old female with well-controlled type 2 diabetes mellitus who presented to the emergency department with a history of shortness of breath, cough, and weight loss. She denied any use of immunosuppressive medications. High-resolution CT revealed a large right upper lung cavitary lesion, and the sputum examination and bronchoalveolar lavage revealed and positive galactomannan. In conclusion, immunocompetent hosts are rarely affected by aspergilloma with lung cavities. We recommend conducting a retrospective data registry on unreported aspergilloma cases in immunocompetent patients to understand the clinicopathological behavior and improve management.
曲霉病是一种由[未提及具体病因]引起的严重病理状况，通常影响免疫功能低下的患者。近年来，已证明[未提及具体病原体]感染可导致多种肺部疾病，包括变应性支气管肺曲霉病、慢性坏死性曲霉病、曲霉球和侵袭性曲霉病。本病例报告对[未提及具体病原体]感染的各种肺部表现的特征性计算机断层扫描（CT）和病理结果进行了说明和综述。[未提及具体病原体]感染在严重免疫抑制患者中影响肺部的情况并不常见。在本文中，我们报告了一例50岁2型糖尿病控制良好的女性患者，她因呼吸急促、咳嗽和体重减轻的病史就诊于急诊科。她否认使用过任何免疫抑制药物。高分辨率CT显示右上肺有一个大的空洞性病变，痰检和支气管肺泡灌洗发现[未提及具体检查结果]及半乳甘露聚糖阳性。总之，免疫功能正常的宿主很少受到有空洞的曲霉球影响。我们建议对免疫功能正常患者中未报告的曲霉球病例进行回顾性数据登记，以了解其临床病理行为并改善管理。
