Goel Nitin, Spalgais Sonam, Mrigpuri Parul, Khanna Madhu, Menon Balakrishnan, Kumar Raj
Department of Pulmonary Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi.
Virology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi.
Monaldi Arch Chest Dis. 2020 Nov 9;90(4). doi: 10.4081/monaldi.2020.1568.
The pandemic of COVID-19 has emerged as a serious health crisis globally and India too has been extensively affected with 604,641 active cases reported, till date. The present study focuses on the demographic, clinical and laboratory profile of such patients from a tertiary level non-COVID respiratory care hospital. This is a retrospective observational study. Seventy-seven sick patients fulfilling COVID suspect criteria were admitted to the isolation area. Their RT-PCR test was done from the designated laboratory and 35 of them were confirmed to be COVID-19 patients. The detailed demographic, clinical and laboratory profile of these COVID-19 patients was studied. The mean age was 46±17 years with male predominance (57%). Majority of the cases (83%) were symptomatic. The most common symptom was cough (66%) followed by breathlessness and fever. Nineteen (54.3%) patients had one or the other co-morbidity and 16 (45.7%) had chronic lung diseases as one of the comorbidities. Nearly half of the patients (51%) required supplementary oxygen on presentation. Two patients were put on invasive mechanical ventilation while 4 patients required non-invasive ventilation before being shifted to the COVID hospital. Hence, it can be concluded that COVID-19 in patients of chronic respiratory diseases manifests with higher prevalence of symptoms and also higher severity of disease. Further, the symptomatology of COVID-19 closely mimics the acute exacerbation of chronic lung diseases, so cautious screening and testing should be done, especially at the pulmonary department.
新型冠状病毒肺炎疫情已成为全球严重的健康危机,印度也受到了广泛影响,截至目前已报告604641例确诊病例。本研究聚焦于一家三级非新冠呼吸道护理医院此类患者的人口统计学、临床和实验室特征。这是一项回顾性观察研究。77名符合新冠疑似标准的患者被收治到隔离区。他们的逆转录聚合酶链反应(RT-PCR)检测由指定实验室完成,其中35人被确诊为新型冠状病毒肺炎患者。对这些新型冠状病毒肺炎患者的详细人口统计学、临床和实验室特征进行了研究。平均年龄为46±17岁,男性占多数(57%)。大多数病例(83%)有症状。最常见的症状是咳嗽(66%),其次是呼吸急促和发热。19名(54.3%)患者有一种或多种合并症,16名(45.7%)患者有慢性肺部疾病作为合并症之一。近一半患者(51%)就诊时需要补充氧气。两名患者接受了有创机械通气,4名患者在转至新冠医院之前需要无创通气。因此,可以得出结论,慢性呼吸道疾病患者的新型冠状病毒肺炎表现为症状发生率较高且疾病严重程度也较高。此外,新型冠状病毒肺炎的症状学与慢性肺部疾病的急性加重极为相似,因此应进行谨慎的筛查和检测,尤其是在肺部疾病科。