Department of Veterinary Science, University of Parma, 43126 Parma, Italy.
Department of Veterinary Science, University of Pisa, 56124 Pisa, Italy.
Toxins (Basel). 2020 Nov 8;12(11):706. doi: 10.3390/toxins12110706.
Ochratoxin A (OTA) is a mycotoxin produced by and , capable of contaminating several foodstuffs. OTA damages primarily the kidneys, and is suspected to be a carcinogenic substance, thus maximum levels for OTA in foodstuffs have been established in the EU. Italian Ministry of Health suggested a maximum level of 1 μg/kg OTA in pork meat and derived products. In this study, OTA concentrations in liver, kidney, and muscle of 64 wild boars () killed in two areas (area A and B) of Parma province (northern Italy), characterized by different habitat types, were assessed by HPLC-FLD technique. OTA was detected in 54% liver, 52% kidney, and 16% muscle samples. OTA levels were significantly higher in liver and kidney compared with muscle, and were above 1 μg/kg in 19 liver, 17 kidney, and 4 muscle samples. OTA levels in wild boars from area A resulted significantly higher with respect to those from area B, suggesting an environmental influence on OTA contamination in wild boars. This study seems to confirm that wild boar meat is a potential source of OTA, thus monitoring the presence of this mycotoxin in game meat might be recommended to prevent risks for human health.
赭曲霉毒素 A(OTA)是一种由曲霉菌和青霉菌产生的霉菌毒素,能够污染多种食品。OTA 主要损害肾脏,并被怀疑是一种致癌物质,因此欧盟已经为食品中的 OTA 制定了最大限量标准。意大利卫生部建议在猪肉及其制品中 OTA 的最大限量为 1μg/kg。本研究采用 HPLC-FLD 技术检测了在意大利北部帕尔马省(Parma province)两个不同生境类型地区(A 区和 B 区)猎捕的 64 头野猪(Sus scrofa)的肝脏、肾脏和肌肉中 OTA 的浓度。OTA 在 54%的肝脏、52%的肾脏和 16%的肌肉样本中被检测到。OTA 在肝脏和肾脏中的水平明显高于肌肉,19 个肝脏、17 个肾脏和 4 个肌肉样本中的 OTA 水平超过 1μg/kg。A 区野猪的 OTA 水平明显高于 B 区,表明环境对野猪中 OTA 污染有影响。本研究似乎证实了野猪肉是 OTA 的潜在来源,因此建议对野味中这种霉菌毒素的存在进行监测,以防止对人类健康造成风险。