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纳米容器在药物传递系统中的应用:埃洛石纳米管及其性能综述。

Nanocontainers for drug delivery systems: A review of Halloysite nanotubes and their properties.

机构信息

Department of Biomedical Engineering, Central Tehran Branch, Islamic Azad University, IAUCTB, Tehran, Iran.

Department of Chemistry, Amirkabir University of Technology, Tehran, Iran.

出版信息

Int J Artif Organs. 2021 Jun;44(6):426-433. doi: 10.1177/0391398820968836. Epub 2020 Nov 10.

DOI:10.1177/0391398820968836
PMID:33172333
Abstract

Halloysite nanotubes (HNTs) are known as inexpensive and available nanomaterials that are rich in functionality, environmentally benign, and also safe and easy to process. As well, good particle size (i.e. nanoscale) and perfect tubular microstructures of these materials make them to be used extensively as drug carriers. Also, the unique physical and chemical properties of their internal and external surfaces are the greatest priority for the drug encapsulation controlling and releasing. In this review, is tried to emphasis on the main properties of HNTs to manage and develop effective drug delivery tools in the biomedical and pharmaceutical fields.

摘要

海泡石纳米管 (HNTs) 是一种廉价且易得的纳米材料,具有丰富的功能性、环境友好性、安全性和易于加工等特点。此外,这些材料具有良好的粒径(即纳米级)和完美的管状微观结构,因此被广泛用作药物载体。此外,其内外表面的独特物理化学性质是控制和释放药物包封的首要任务。在本文综述中,重点介绍了 HNTs 的主要性质,以管理和开发生物医学和制药领域的有效药物输送工具。

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