Odell J M, Allen J K, Badura R J, Weinberger E
Department of Pediatrics, Children's Hospital and Medical Center, Washington 98105.
Pediatr Pathol. 1987;7(3):333-40. doi: 10.1080/15513818709177134.
Although intracranial teratoma is a well-recognized entity in the differential diagnosis of pediatric brain tumors, massive congenital intracranial teratoma replacing the cerebral hemispheres of a neonate has seldom been reported. We describe two such instances that histologically exhibit predominantly neuroepithelial differentiation. In 1 case serial prenatal ultrasonography revealed ventricular dilatation prior to identification of the lesion. Theories of pathogenesis are briefly discussed.
尽管颅内畸胎瘤在小儿脑肿瘤的鉴别诊断中是一个广为人知的实体，但很少有报道称巨大的先天性颅内畸胎瘤取代新生儿的大脑半球。我们描述了两例这样的病例，其组织学表现主要为神经上皮分化。在1例中，产前系列超声检查在发现病变之前显示脑室扩张。对发病机制的理论进行了简要讨论。
