Oi S, Tamaki N, Kondo T, Nakamura H, Kudo H, Suzuki H, Sasaki M, Matsumoto S, Ueda Y, Katayama K
Department of Neurosurgery, Kobe University School of Medicine, Japan.
Childs Nerv Syst. 1990 Dec;6(8):459-61. doi: 10.1007/BF00302094.
The authors describe a case of congenital intracranial teratoma. The patient was diagnosed to be hydrocephalic at 29 weeks' gestation, and to have a huge intraventricular mass lesion at 34 weeks' gestation. Subsequently, the patient underwent subtotal resection of the mass, resulting in a significant decrease in the remarkably elevated alpha-fetoprotein in serum and cerebrospinal fluid. Histological analysis revealed a malignant teratoma, also with alpha-fetoprotein-positive elements in the immunohistochemical study.
作者描述了一例先天性颅内畸胎瘤病例。该患者在妊娠29周时被诊断为脑积水，在妊娠34周时发现有巨大的脑室内肿块病变。随后，患者接受了肿块次全切除术，血清和脑脊液中显著升高的甲胎蛋白水平大幅下降。组织学分析显示为恶性畸胎瘤，免疫组化研究中也有甲胎蛋白阳性成分。
