Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada.
Women's College Research Institute, Women's College Hospital, 76 Grenville St., 6th Floor, Toronto, ON, M5S 1B2, Canada.
Breast Cancer Res Treat. 2021 Feb;186(1):177-189. doi: 10.1007/s10549-020-05992-w. Epub 2020 Nov 10.
Many women with early-onset breast cancer experience adverse psychological sequelae which impact on their quality of life. We sought to correlate levels of anxiety and cancer-related distress in women with breast cancer shortly after surgery and one year after treatment with the estimated risk of death.
We studied 596 women with Stage I to III breast cancer. For each woman we estimated the five-year risk of death based on SEER data from 2010 to 2019. For each woman we measured anxiety and cancer-related distress levels shortly after surgery and one year later.
The mean estimated five-year survival was 95%. At one week post-surgery, 59% of women had a clinically significant level of anxiety and 74% had a clinically significant level of cancer-related distress. There was no correlation between the objective risk of death and the level of anxiety or distress, at one week or at one year.
Many women diagnosed with early-stage breast cancers experience significant levels of anxiety and distress. The emotional response to a breast cancer diagnosis is not related to the risk of death per se and other factors should be explored.
许多早期乳腺癌患者会出现不良心理后果，影响其生活质量。我们试图将女性在手术后不久和治疗一年后乳腺癌相关焦虑和困扰的水平与预计的死亡风险相关联。
我们研究了 596 例 I 期至 III 期乳腺癌患者。对于每位女性，我们根据 2010 年至 2019 年 SEER 数据估计了五年的死亡风险。对于每位女性，我们在手术后不久和一年后测量了焦虑和癌症相关困扰的水平。
平均估计五年生存率为 95%。手术后一周，59%的女性有明显的焦虑水平，74%的女性有明显的癌症相关困扰。在一周或一年时，客观死亡风险与焦虑或困扰水平之间没有相关性。
许多被诊断为早期乳腺癌的女性经历了严重的焦虑和困扰。对乳腺癌诊断的情绪反应与死亡风险本身无关，应该探索其他因素。
