Women's College Research Institute, Women's College Hospital, Toronto, ON M5S 1B2, Canada.
Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada.
Curr Oncol. 2022 Jul 13;29(7):4936-4940. doi: 10.3390/curroncol29070392.
At present, women with ductal carcinoma in situ are counseled that they have a pre-malignant condition which carries the possibility of progression to a fully malignant breast cancer. However, in most cases, the treatment of DCIS resembles that of a small invasive breast cancer and this is a source of confusion to many. In order to properly evaluate the benefit of radiotherapy, mastectomy and contralateral mastectomy, it is necessary to consider the risks of ipsilateral invasive cancer and of contralateral breast cancer in women with DCIS and with small invasive breast cancer. Several registry-based studies indicate that the risks of ipsilateral and contralateral cancer are similar in the two conditions and therefore a similar approach to treatment is rational.
目前，患有导管原位癌的女性被告知她们患有癌前病变，有可能发展为完全恶性的乳腺癌。然而，在大多数情况下，DCIS 的治疗类似于小侵袭性乳腺癌，这让许多人感到困惑。为了正确评估放疗、乳房切除术和对侧乳房切除术的益处，有必要考虑患有 DCIS 和小侵袭性乳腺癌的女性同侧浸润性癌和对侧乳腺癌的风险。几项基于登记的研究表明，这两种情况下同侧和对侧癌症的风险相似，因此采用类似的治疗方法是合理的。
