咽后壁结核——一种被忽视的形似恶性肿瘤的疾病。
Posterior Pharyngeal Wall Tuberculosis-A Forgotten Entity Mimicking Malignancy.
机构信息
Department of Otolaryngology and Head-Neck Surgery, 28730All India Institute of Medical Sciences, New Delhi, India.
Department of Nuclear Medicine, 28730All India Institute of Medical Sciences, New Delhi, India.
出版信息
Ear Nose Throat J. 2022 Nov;101(9):578-580. doi: 10.1177/0145561320973781. Epub 2020 Nov 11.
BACKGROUND
Tuberculosis (TB) of posterior pharyngeal wall (PPW), either primary or secondary, is extremely rare and can mimic malignancy in elderly patients.
CASE REPORT
A 36-year-old female patient presented with complains of nonhealing ulcer at the back of her throat for 4 months. On examination, there was an ulceroproliferative growth covered with slough over PPW. Positron emission tomography scan showed uptake in PPW. There was no uptake in any other part of body. A biopsy from PPW lesion showed epithelioid cell granulomas with Langhans type giant cells. Auramine-rhodamine staining showed few beaded bacilli consistent with TB.
CONCLUSION
Tuberculosis of PPW is an extremely uncommon entity and can mimic malignancy. It should be kept as one of the differential diagnosis as it can be cured solely by giving anti-tubercular therapy.
背景
无论是原发性还是继发性，咽后壁（PPW）结核都极为罕见，并且在老年患者中可能类似于恶性肿瘤。
病例报告
一名 36 岁女性患者因咽喉后部的不愈溃疡而就诊，病程为 4 个月。检查发现，PPW 上覆盖着有坏死组织的溃疡增生性生长物。正电子发射断层扫描显示 PPW 摄取。身体的其他任何部位均无摄取。PPW 病变的活检显示上皮样细胞肉芽肿伴郎汉斯型巨细胞。金胺罗丹明染色显示有少量串珠状杆菌，符合结核。
结论
PPW 结核是一种极为罕见的疾病，可与恶性肿瘤相类似。它应该作为鉴别诊断之一，因为仅通过给予抗结核治疗即可治愈。
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