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HIV 背景下咽部原发性结核:一例报告

Primary Tuberculosis of the Pharynx in an HIV Context: A Case Report.

作者信息

Morán-Mariños Cristian, Llanos-Tejada Felix, Villanueva-Villegas Renzo, Vargas-Ponce Kanneth G, Salas-López Juan

机构信息

Unidad Especializada en Tuberculosis, Servicio de Neumología, Hospital Nacional Dos de Mayo, Lima, Perú.

Unidad de Investigación en Bibliometría, Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Perú.

出版信息

Clin Med Insights Case Rep. 2024 May 5;17:11795476241251945. doi: 10.1177/11795476241251945. eCollection 2024.

Abstract

Pharyngeal tuberculosis without pulmonary involvement is very rare and may be confused with malignant lesions. We present a 45-year-old female patient with a history of HIV presenting with a history of cough, sore throat, and oral ulcers with chronic use of antibiotics. The evolution would indicate a probable malignant tumor, but the biopsy was consistent with Pharyngeal TB. The patient initiated anti-tuberculosis therapy and demonstrated improved conditions and remission of ulcers. In the context of HIV, this treatment could be a major contributor to the underdiagnosis of the disease and may lead to alternative diagnoses. Therefore, it is vital to consider this condition in patients who do not respond to antibiotics.

摘要

无肺部受累的咽结核非常罕见,可能会与恶性病变相混淆。我们报告一名45岁的女性患者,有HIV病史,伴有咳嗽、咽痛和口腔溃疡病史,长期使用抗生素。病情发展提示可能为恶性肿瘤,但活检结果与咽结核相符。患者开始接受抗结核治疗,病情改善,溃疡缓解。在HIV感染的背景下,这种治疗可能是导致该疾病诊断不足的一个主要因素,可能会导致其他诊断结果。因此,对于对抗生素无反应的患者,考虑这种情况至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95d6/11072070/7a0da5f3e649/10.1177_11795476241251945-fig1.jpg

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