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法国首例新冠肺炎疫情爆发对肝移植活动的影响:快照。

Impact of the first Covid-19 outbreak on liver transplantation activity in France: A snapshot.

机构信息

Department of Digestive, Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Pitié-Salpêtrière Hospital, Paris, France; Department of Digestive and Oncologic Surgery, Liver Transplantation Unit, University Hospital of Besançon, Besançon, France.

Department of Digestive, Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Pitié-Salpêtrière Hospital, Paris, France.

出版信息

Clin Res Hepatol Gastroenterol. 2021 Jul;45(4):101560. doi: 10.1016/j.clinre.2020.10.005. Epub 2020 Nov 8.

DOI:10.1016/j.clinre.2020.10.005
PMID:33176991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7649029/
Abstract

BACKGROUND

The global pandemic of Coronavirus Disease 2019 (COVID-19) has potentially affected liver transplantation (LT) programs worldwide. The aim of this study was to determine whether the COVID-19 outbreak affected organ donation and LT activity in France.

METHODS

Data on the number of brain-dead donor procurements and adult liver transplantations were compared between two periods (1 January- 31 May 2019 vs. 1 January-31 May 2020).

MAIN FINDINGS

There was a 28% decrease in the number of organ donations in 2020 (543 in 2020vs. 752 organ donations in 2019). A 22% decrease in the number of liver transplantations was also observed: 435 in 2020 vs. 556 LTs in 2019. Overall, the North East area which was the main COVID-19 cluster area, had > 25% decrease of the multiorgan procurement (-33% compared to 2019), and liver transplantation (-26% compared to 2019) activities in 2020 CONCLUSION: This analysis confirmed that during the COVID-19 outbreak there was a significant decrease in the number of organ donations and liver transplantations performed in France.

摘要

背景

2019 年冠状病毒病(COVID-19)的全球大流行可能已经影响了全球的肝移植(LT)计划。本研究旨在确定 COVID-19 疫情是否影响了法国的器官捐赠和 LT 活动。

方法

比较了两个时期(2019 年 1 月 1 日至 5 月 31 日与 2020 年 1 月 1 日至 5 月 31 日)的脑死亡供体采集数量和成人肝移植数量。

主要发现

2020 年器官捐献数量下降了 28%(2020 年为 543 例,而 2019 年为 752 例)。肝移植数量也下降了 22%:2020 年为 435 例,而 2019 年为 556 例。总体而言,东北地区是 COVID-19 的主要聚集区,2020 年多器官采集活动减少了>25%(与 2019 年相比减少了 33%),肝移植活动减少了 26%(与 2019 年相比减少了 26%)。

结论

本分析证实,在 COVID-19 疫情期间,法国的器官捐赠数量和进行的肝移植数量显著减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/7f7ebf02bc9e/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/cd983ab3736d/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/850618f1ccf9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/44dc591dafc1/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/7f7ebf02bc9e/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/cd983ab3736d/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/850618f1ccf9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/44dc591dafc1/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecbe/7649029/7f7ebf02bc9e/gr4_lrg.jpg

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