韩国新冠疫情期间肝肾移植数量分析。

An analysis of the number of liver and kidney transplantations during COVID-19 pandemic in Korea.

作者信息

Hong Jung-Ja, Hwang Shin, Moon Deog-Bok, Kim Young Hoon, Shin Sung, Kim In-Ok, Lee Sae-Rom, Lee Ah-Young, Woo Jiwon

机构信息

Organ Transplantation Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Korean J Transplant. 2021 Dec 31;35(4):247-252. doi: 10.4285/kjt.21.0030.

DOI:10.4285/kjt.21.0030

PMID:35769853

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9235458/

Abstract

BACKGROUND

The severity of the coronavirus disease 2019 (COVID-19) pandemic has discouraged organ donation. However, the prevalence of COVID-19 in Korea was much lower in comparison to Western countries. With this, the authors decided to determine the real-world impact of COVID-19 on organ donation and transplantation in Korea.

METHODS

The number of kidney transplantations (KTs) and liver transplantations (LTs) performed in 2020 were compared with those in 2019 using the Korean Network for Organ Sharing database and Asan Medical Center (AMC) database.

RESULTS

The annual number of deceased donors (DDs) was 450 in 2019 compared to 478 in 2020. Monthly DD number was 37.5±5.9 in 2019 and 39.8±4.4 in 2020 (P=0.284). Annual number of DD kidney transplant (DDKT) was 794 in 2019 and 848 in 2020, and monthly number was 66.1±10.4 in 2019 and 70.7±9.8 in 2020 (P=0.285). The annual number of DDLT was 391 in 2019 and 395 in 2020, and the monthly number was 32.6±5.7, 2019 and 32.9±4.7 in 2020 (P=0.877). The annual number of living donor (LD) KT was 2,293 in 2019 and 1,432 in 2020, and the monthly number was 191.1±19.5 in 2019 and 119.3±11.7 in 2020 (P<0.001). Annual number of living donor LDLT was 1,577 in 2019 and 1,146 in 2020, and monthly number was 131.4±18.1 in 2019 and 95.5±8.0 in 2020 (P<0.001). In the AMC, not all types of KT and LT changed significantly.

CONCLUSIONS

The results of this study indicate that the number of DD organ transplantations remained stable in Korea in 2020, but the number of LD organ transplantations was significantly reduced. However, the number of organ transplantations did not change in the AMC.

摘要

背景

2019年冠状病毒病（COVID-19）大流行的严重程度阻碍了器官捐赠。然而，与西方国家相比，韩国COVID-19的患病率要低得多。据此，作者决定确定COVID-19对韩国器官捐赠和移植的实际影响。

方法

使用韩国器官共享网络数据库和峨山医院（AMC）数据库，将2020年进行的肾移植（KT）和肝移植（LT）数量与2019年的进行比较。

结果

2019年已故捐赠者（DD）的年度数量为450人，2020年为478人。2019年月度DD数量为37.5±5.9，2020年为39.8±4.4（P=0.284）。2019年DD肾移植（DDKT）的年度数量为794例，2020年为848例，2019年月度数量为66.1±10.4，2020年为70.7±9.8（P=0.285）。2019年DDLT的年度数量为391例，2020年为395例，2019年月度数量为32.6±5.7，2020年为32.9±4.7（P=0.877）。2019年活体捐赠者（LD）KT的年度数量为2293例，2020年为1432例，2019年月度数量为191.1±19.5，2020年为119.3±11.7（P<0.001）。2019年活体捐赠者LDLT的年度数量为1577例，2020年为1146例，2019年月度数量为131.4±18.1，2020年为95.5±8.0（P<0.001）。在AMC，并非所有类型的KT和LT都有显著变化。