Yokobori A Toshimitsu
Strategic Innovation and Research Center, Teikyo University.
Proc Jpn Acad Ser B Phys Biol Sci. 2020;96(9):373-393. doi: 10.2183/pjab.96.029.
In this work, the mesoscale mechanics of metals, which links their microscopic physics and macroscopic mechanics, was established. For practical applications, the laws for quantitatively predicting life of cycle and time-dependent fracture behavior such as fatigue, hydrogen embrittlement, and high-temperature creep were derived using particle transport phenomena theories such as dislocation group dynamics, hydrogen diffusion, and vacancy diffusion. Furthermore, these concepts were also applied for estimating the degree of viscoelastic deterioration of blood vessel walls, which is dominated by a time-dependent mechanism, and for the diagnosis of aneurysm accompanied by the viscoelastic deterioration of the blood vessel wall. In these theories, new mechanical indexes were derived as dominant factors for predicting the life of fatigue crack growth and the time-dependent fracture of notched specimens of materials such as hydrogen embrittlement and high-temperature creep. Furthermore, as an example of a practical application, these theories were applied to estimate the degree of viscoelastic deterioration and chaotic motions of blood vessel walls, which are closely related to blood vessel diseases such as atherosclerosis and aneurysm. Moreover, new indexes to diagnose them were also proposed for clinical applications.
在这项工作中,建立了连接金属微观物理和宏观力学的中尺度力学。在实际应用方面,利用诸如位错群动力学、氢扩散和空位扩散等粒子输运现象理论,推导出了定量预测循环寿命以及疲劳、氢脆和高温蠕变等与时间相关的断裂行为的规律。此外,这些概念还被应用于估计以时间相关机制为主导的血管壁粘弹性劣化程度,以及诊断伴有血管壁粘弹性劣化的动脉瘤。在这些理论中,推导了新的力学指标作为预测疲劳裂纹扩展寿命以及氢脆和高温蠕变等材料缺口试样与时间相关断裂的主导因素。此外,作为实际应用的一个例子,这些理论被应用于估计与动脉粥样硬化和动脉瘤等血管疾病密切相关的血管壁粘弹性劣化程度和混沌运动。此外,还提出了用于临床应用的诊断这些疾病的新指标。