Kesserwani Hassan
Neurology, Flowers Medical Group, Dothan, USA.
Cureus. 2020 Oct 10;12(10):e10881. doi: 10.7759/cureus.10881.
Dizziness can be protean with multiple phenotypes. One common phenotype in the young population is postural orthostatic tachycardia syndrome (POTS). POTS has a unique cardiovascular signature with a fascinating range of etiologies and pharmacodynamic substrates. This condition can pass undiagnosed for many years and is often mistaken as an anxiety disorder due to some of its hyperadrenergic manifestations. We present one such case and then flesh out the treatment strategies, both conservative and pharmacologic. We finally describe the various underlying pathophysiologic mechanisms of POTS and its sub-types and outline the various aberrant cardiovascular reflexes. We also describe the power spectra of the heart rate variability frequency bands and their underlying physiologic basis.
头晕症状多样，具有多种表现型。在年轻人群中，一种常见的表现型是体位性直立性心动过速综合征（POTS）。POTS具有独特的心血管特征，病因范围广泛，药效学基础引人关注。这种病症可能多年未被诊断出来，由于其一些高肾上腺素能表现，常被误诊为焦虑症。我们呈现这样一个病例，然后详细阐述保守治疗和药物治疗策略。最后，我们描述POTS及其亚型的各种潜在病理生理机制，概述各种异常的心血管反射。我们还描述心率变异性频段的功率谱及其潜在的生理基础。
