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前列腺的现代成像与图像引导治疗:用于癌症的磁共振成像和消融以及用于良性前列腺增生的前列腺动脉栓塞术。

Modern imaging and image-guided treatments of the prostate gland: MR and ablation for cancer and prostatic artery embolization for benign prostatic hyperplasia.

作者信息

Dias João Lopes, Bilhim Tiago

出版信息

BJR Open. 2019 Aug 14;1(1):20190019. doi: 10.1259/bjro.20190019. eCollection 2019.

Abstract

Multiparametric MRI (mpMRI) has proven to be an essential tool for diagnosis, post-treatment follow-up, aggressiveness assessment, and active surveillance of prostate cancer. Currently, this imaging technique is part of the daily practice in many oncological centres. This manuscript aims to review the use of mpMRI in the set of prostatic diseases, either malignant or benign: mpMRI to detect and stage prostate cancer is discussed, as well as its use for active surveillance. Image-guided ablation techniques for prostate cancer are also reviewed. The need to establish minimum acceptable technical parameters for prostate mpMRI, standardize reports, uniform terminology for describing imaging findings, and develop assessment categories that differentiate levels of suspicion for clinically significant prostate cancer led to the development of the Prostate Imaging Reporting and Data System that is reviewed. Special focus will also be given on the most up-to-date evidence of prostatic artery embolization (PAE) for symptomatic benign prostatic hyperplasia (BPH). Management of patients with BPH, technical aspects of PAE, expected outcomes and level of evidence are reviewed with the most recent literature. PAE is a challenging technique that requires dedicated anatomical knowledge and comprehensive embolization skills. PAE has been shown to be an effective minimally-invasive treatment option for symptomatic BPH patients, that can be viewed between medical therapy and surgery. PAE may be a good option for symptomatic BPH patients that do not want to be operated and can obviate the need for prostatic surgery in up to 80% of treated patients.

摘要

多参数磁共振成像(mpMRI)已被证明是前列腺癌诊断、治疗后随访、侵袭性评估及主动监测的重要工具。目前,这种成像技术是许多肿瘤中心日常诊疗的一部分。本文旨在综述mpMRI在一系列前列腺疾病(包括恶性和良性)中的应用:讨论了mpMRI用于检测前列腺癌及分期,以及其在主动监测中的应用。还综述了前列腺癌的图像引导消融技术。由于需要为前列腺mpMRI建立最低可接受的技术参数、规范报告、统一描述影像表现的术语,并制定区分临床显著性前列腺癌可疑程度的评估类别,从而催生了前列腺影像报告和数据系统并对其进行了综述。还将特别关注症状性良性前列腺增生(BPH)的前列腺动脉栓塞术(PAE)的最新证据。结合最新文献对BPH患者的管理、PAE的技术方面、预期结果及证据水平进行了综述。PAE是一项具有挑战性的技术,需要专门的解剖学知识和全面的栓塞技能。PAE已被证明是症状性BPH患者有效的微创治疗选择,可介于药物治疗和手术之间。对于不想接受手术的症状性BPH患者,PAE可能是一个不错的选择,并且在高达80%的接受治疗的患者中可避免前列腺手术的需要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b1/7592499/6465f3104a3f/bjro.20190019.g001.jpg

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