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细菌植物病原体的群体基因组学。

Population Genomics of Bacterial Plant Pathogens.

机构信息

Institute of Environmental Science and Research, Health and Environment, Auckland, New Zealand.

Genomics Aotearoa, New Zealand.

出版信息

Phytopathology. 2021 Jan;111(1):23-31. doi: 10.1094/PHYTO-09-20-0412-RVW. Epub 2020 Dec 11.

DOI:10.1094/PHYTO-09-20-0412-RVW
PMID:33179999
Abstract

Population genomics is transforming our understanding of pathogen biology and evolution, and contributing to the prevention and management of disease in diverse crops. We provide an overview of key methods in bacterial population genomics and describe recent work focusing on three topics of critical importance to plant pathology: (i) resolving pathogen origins and transmission pathways during outbreak events, (ii) identifying the genetic basis of host specificity and virulence, and (iii) understanding how pathogens evolve in response to changing agricultural practices.[Formula: see text] Copyright © 2021 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license.

摘要

人口基因组学正在改变我们对病原体生物学和进化的理解,并有助于预防和管理各种作物的疾病。我们提供了细菌种群基因组学的主要方法的概述,并描述了最近的工作,重点关注植物病理学三个至关重要的主题:(i)在爆发事件中解决病原体的起源和传播途径,(ii)确定宿主特异性和毒力的遗传基础,以及(iii)了解病原体如何应对不断变化的农业实践而进化。[公式:见正文] 版权所有 © 2021 作者。这是一个在 CC BY-NC-ND 4.0 国际许可下发布的开放获取文章。

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