Department of Mathematics, School of Sciences and Engineering, University of Asia and the Pacific, Pasig City, Philippines.
Mathematics and Statistics Department, De La Salle University, Manila, Philippines.
Methods Mol Biol. 2021;2189:157-167. doi: 10.1007/978-1-0716-0822-7_12.
Mathematical models for the spread of diseases help us understand the mechanisms on how diseases spread, evaluate the possible effects of interventions, predict outcomes of epidemics, and forecast the course of outbreaks. Compartmental models are widely used in synthetic biology since they can represent a biological system as an assembly of various parts or compartments with different functions. Here we present a framework for the analysis of a compartmental model for the transmission of diseases using ordinary differential equations. We apply this method on a study about the spread of tuberculosis.
疾病传播的数学模型帮助我们理解疾病传播的机制，评估干预措施的可能效果，预测传染病的结果，并预测疫情的发展。由于可以将生物系统表示为具有不同功能的各种部分或隔室的集合，因此房室模型在合成生物学中得到了广泛应用。在这里，我们提出了一种使用常微分方程分析疾病传播房室模型的框架。我们将这种方法应用于一项关于结核病传播的研究。
