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基于手术方式的直肠阴道瘘修补术的围手术期结果:一项全国性的当代分析。

Perioperative Outcomes of Rectovaginal Fistula Repair Based on Surgical Approach: A National Contemporary Analysis.

机构信息

From the Department of Obstetrics and Gynecology.

Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery Surgical Outcomes Program, Mayo Clinic, Rochester, MN.

出版信息

Female Pelvic Med Reconstr Surg. 2021 Feb 1;27(2):e342-e347. doi: 10.1097/SPV.0000000000000924.

Abstract

OBJECTIVE

To compare the perioperative outcomes of transvaginal/perineal and abdominal approaches to rectovaginal fistula (RVF) repair using a national multicenter cohort.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program database was utilized to identify women undergoing RVF repair from 2005 to 2016. Emergent cases and those with concomitant bowel diversion were excluded. Baseline patient demographics, procedure characteristics, 30-day postoperative complications, return to the operating room, and readmission were evaluated. Baseline characteristics were compared across surgical approach. Multivariable logistic regression models identified preoperative characteristics independently associated with postoperative complications.

RESULTS

A total of 2288 women underwent RVF repair: 1560 (68.2%) via transvaginal/perineal approach and 728 (31.8%) via abdominal approach. Patients undergoing transvaginal/perineal repair were significantly younger (median age, 46 years vs 63 years), with lower American Society for Anesthesiologist (ASA) scores, and less frequency of diabetes mellitus, dyspnea, severe chronic obstructive pulmonary disease, hypertension, disseminated cancer, and bleeding disorders (all P < 0.01). Those undergoing abdominal repair had higher rates of major complications (25.8% vs 8.7%), minor complications (13.5% vs 6.3%), and readmission (13.2% vs 7.8%). On multivariable analyses, ASA Class 3/4, disseminated cancer, and hematocrit <30% (P < 0.01) were associated with major complications in both groups.

CONCLUSIONS

Patients undergoing RVF repair via abdominal approach were older with more comorbidities and had higher postoperative complications rates, likely secondary to underlying differences in the treated populations. Irrespective of surgical approach, ASA class, disseminated cancer, and preoperative anemia were associated with higher postoperative morbidity. This may enhance preoperative counseling and allow for careful patient selection.

摘要

目的

利用国家多中心队列比较经阴道/会阴和腹部途径修复直肠阴道瘘(RVF)的围手术期结果。

方法

利用美国外科医师学会国家手术质量改进计划数据库,确定 2005 年至 2016 年期间接受 RVF 修复的女性。排除急症病例和伴有肠转流的病例。评估基线患者人口统计学特征、手术特点、30 天术后并发症、再次手术和再入院。比较手术方法的基线特征。多变量逻辑回归模型确定与术后并发症独立相关的术前特征。

结果

共有 2288 名女性接受 RVF 修复:1560 名(68.2%)经阴道/会阴途径,728 名(31.8%)经腹部途径。经阴道/会阴修复的患者年龄明显较小(中位数年龄 46 岁比 63 岁),美国麻醉医师协会(ASA)评分较低,糖尿病、呼吸困难、严重慢性阻塞性肺疾病、高血压、播散性癌症和出血性疾病的频率较低(均 P < 0.01)。接受腹部修复的患者主要并发症(25.8%比 8.7%)、小并发症(13.5%比 6.3%)和再入院(13.2%比 7.8%)的发生率更高。多变量分析显示,ASA 分级 3/4、播散性癌症和血细胞比容<30%(P < 0.01)与两组的主要并发症相关。

结论

接受腹部 RVF 修复的患者年龄较大,合并症较多,术后并发症发生率较高,可能与治疗人群的潜在差异有关。无论手术途径如何,ASA 分级、播散性癌症和术前贫血与术后发病率较高相关。这可能增强术前咨询,并允许仔细选择患者。

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