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甲状腺切除术对生活质量有何影响:甲状腺切除术后患者与普通人群匹配个体的回顾性病例对照研究。

Does Thyroidectomy Impact Quality of Life: Retrospective Case-Control Study of Post-Thyroidectomy Patients and Matched Individuals from the General Population.

作者信息

Yu Hyeong Won, An Ah Reum, Kang Hye In, Suh Yong Joon, Kwon Hyungju, Kim Su-Jin, Chai Young Jun, Choi June Young, Choi Hochun, Lee Kyu Eun, Cho Belong

机构信息

Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si 13620, Korea.

Department of Family Medicine, Seoul National University Hospital Healthcare System Gangnam Center and College of Medicine, Seoul 06236, Korea.

出版信息

Medicina (Kaunas). 2020 Nov 10;56(11):603. doi: 10.3390/medicina56110603.

DOI:10.3390/medicina56110603
PMID:33182641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7697461/
Abstract

The study assesses quality of life (QoL) in patients who underwent thyroidectomy compared to the general population. QoL data from post-thyroidectomy patients and individuals with no subjective health concerns, who had attended a routine health screening visit, were evaluated. QoL was assessed using the modified version of Korean Short Form 12 questionnaire (SF-12). Patients and controls were matched using the propensity score approach and a ratio of 1:4. Data from a total of 105 patients and 420 controls were analyzed. For five SF-12 items, lower QoL was found in patients ( < 0.05). Multivariate analysis revealed that a follow-up duration of <1-year, female sex, and an age of >50 years were independent risk factors. No significant difference was found between controls and patients who were >1-year post-surgery. For specific SF-12 items, QoL was lower in post-thyroidectomy patients than in controls. No intergroup difference in QoL was found >1-year post-surgery.

摘要

本研究评估了接受甲状腺切除术的患者与普通人群相比的生活质量(QoL)。对甲状腺切除术后患者以及参加常规健康筛查且无主观健康问题的个体的生活质量数据进行了评估。使用韩国简短健康调查问卷(SF - 12)的修订版评估生活质量。采用倾向评分法以1:4的比例对患者和对照组进行匹配。共分析了105例患者和420例对照的数据。在SF - 12的五个项目中,患者的生活质量较低(<0.05)。多变量分析显示,随访时间<1年、女性以及年龄>50岁是独立危险因素。术后>1年的对照组和患者之间未发现显著差异。对于特定的SF - 12项目,甲状腺切除术后患者的生活质量低于对照组。术后>1年未发现组间生活质量差异。

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本文引用的文献

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2
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Oral Oncol. 2015 Jun;51(6):S1-5. doi: 10.1016/j.oraloncology.2015.03.008. Epub 2015 Apr 25.
3
Quality of life in patients with benign nontoxic goiter: impact of disease and treatment response, and comparison with the general population.
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Front Surg. 2023 May 17;10:1116473. doi: 10.3389/fsurg.2023.1116473. eCollection 2023.
良性非毒性甲状腺肿患者的生活质量:疾病及治疗反应的影响,以及与普通人群的比较。
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Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2011.韩国癌症统计数据:2011 年的发病率、死亡率、生存率和流行率。
Cancer Res Treat. 2014 Apr;46(2):109-23. doi: 10.4143/crt.2014.46.2.109. Epub 2014 Apr 22.
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