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Cutaneous Leishmaniasis in the Metropolitan City of Multan, Pakistan, a Neglected Tropical Disease.巴基斯坦木尔坦大都市的皮肤利什曼病,一种被忽视的热带疾病。
J Med Entomol. 2018 Jun 28;55(4):1040-1042. doi: 10.1093/jme/tjy003.
2
Safety and Effectiveness of Sodium Stibogluconate and Paromomycin Combination for the Treatment of Visceral Leishmaniasis in Eastern Africa: Results from a Pharmacovigilance Programme.葡糖酸锑钠与巴龙霉素联合治疗东非内脏利什曼病的安全性和有效性:药物警戒计划的结果
Clin Drug Investig. 2017 Mar;37(3):259-272. doi: 10.1007/s40261-016-0481-0.
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Leishmaniasis worldwide and global estimates of its incidence.全球利什曼病及其发病率的全球估计。
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Two cases of visceral leishmaniasis in Colombia resistant to meglumine antimonial treatment.哥伦比亚两例对葡甲胺锑酸盐治疗耐药的内脏利什曼病病例。
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Diffuse cutaneous leishmaniasis: co-infection with human immunodeficiency virus (HIV).弥漫性皮肤利什曼病:与人类免疫缺陷病毒(HIV)合并感染。
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Multilocus enzyme electrophoresis and cytochrome B gene sequencing-based identification of Leishmania isolates from different foci of cutaneous leishmaniasis in Pakistan.基于多位点酶电泳和细胞色素B基因测序对巴基斯坦不同皮肤利什曼病疫源地利什曼原虫分离株的鉴定
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巴基斯坦开伯尔-普赫图赫瓦省卡拉奇地区山区皮肤利什曼病的流行特征。

Epidemiological features of cutaneous leishmaniasis endemic in hilly areas of district Karak, Khyber-Pakhtunkhwa province of Pakistan.

作者信息

Nawaz Mehboob, Din Misbahud, Khan Ayyaz, Khan Asad, Ali Muhammad, Din Siraj Ud, Aslam Khalid

机构信息

Department of Biotechnology, Quaid-I-Azam University Islamabad, Islamabad, Pakistan.

Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.

出版信息

J Parasit Dis. 2020 Dec;44(4):725-729. doi: 10.1007/s12639-020-01250-4. Epub 2020 Jul 23.

DOI:10.1007/s12639-020-01250-4
PMID:33184539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7596118/
Abstract

Cutaneous leishmaniasis is a vector borne infection caused by flagellated parasitic protozoans of the genus . This is an emergent threat and endemic in areas of tropic and sub-tropics and has a wider geographical distribution. This study was aimed to find the epidemiological aspects of cutaneous leishmaniasis during the recent epidemic in district Karak in 2018-2019. The suspected patients of leishmaniasis from different areas of district Karak were examined. We came across 803 cases during six-month period from August 2018 to January 2019. A major portion (> 37%; n = 299) of these patients were in age 11-20 years. The infection rate was higher in female (55.3%; n = 803) compared to males (44.6%; n = 803). Both gender and age showed a significant effect on the occurrence of infection. It is concluded that cutaneous leishmaniasis has appeared as a major health issue in district Karak. The current study report CL outbreak in Karak district which need immediate response from the healthcare authorities. In addition, extensive awareness campaigns are needed for timely prevention of such outbreaks.

摘要

皮肤利什曼病是由利什曼原虫属的有鞭毛寄生原生动物引起的一种媒介传播感染。这是一种新出现的威胁,在热带和亚热带地区流行,地理分布更广。本研究旨在了解2018 - 2019年卡拉奇地区近期疫情期间皮肤利什曼病的流行病学情况。对来自卡拉奇地区不同区域的疑似利什曼病患者进行了检查。在2018年8月至2019年1月的六个月期间,我们共发现803例病例。这些患者中一大部分(> 37%;n = 299)年龄在11 - 20岁。女性的感染率(55.3%;n = 803)高于男性(44.6%;n = 803)。性别和年龄对感染的发生均有显著影响。得出的结论是,皮肤利什曼病已成为卡拉奇地区的一个主要健康问题。本研究报告了卡拉奇地区的皮肤利什曼病疫情,医疗当局需要立即做出反应。此外,需要开展广泛的宣传活动,以便及时预防此类疫情。