Wittevrongel E, Vranken E, Pepermans A, Jaspers T
Tijdschr Psychiatr. 2020;62(10):901-905.
We describe the case of a 12-year-old boy that developed invalidating motor symptoms after starting and gradually increasing the dose of quetiapine with extended release and phasing out aripiprazole. The symptoms met the definition of tardive dyskinesia given their duration and presentation. Symptoms decreased spontaneously after discontinuation of neuroleptic treatment. The literature and knowledge among clinicians concerning the occurrence of tardive dyskinesia in children and adolescents treated with atypical antipsychotics are limited. We give an overview of the available scientific findings with special attention to the presentation, the incidence and treatment possibilities.
我们描述了一名12岁男孩的病例,该男孩在开始服用缓释喹硫平并逐渐增加剂量、停用阿立哌唑后出现了导致功能丧失的运动症状。鉴于这些症状的持续时间和表现,符合迟发性运动障碍的定义。停用抗精神病药物治疗后,症状自行减轻。关于非典型抗精神病药物治疗的儿童和青少年中迟发性运动障碍发生情况的文献以及临床医生的相关知识有限。我们概述了现有的科学发现,并特别关注其表现、发病率和治疗可能性。