Department of Pathology, Michigan Medicine, Ann Arbor, Michigan, USA.
Department of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
J Cutan Pathol. 2021 May;48(5):632-636. doi: 10.1111/cup.13917. Epub 2020 Nov 29.
Follicle center lymphomas, including primary cutaneous follicle center lymphoma (PCFCL), may rarely show plasmacytic differentiation. Such cases can pose a diagnostic challenge and can be mistaken for other lymphomas that more commonly include plasma cells. Here, we report four cases of PCFCL and one case of systemic follicular lymphoma involving the skin with associated monotypic plasma cells, including the clinical, morphologic and immunophenotypic features.
滤泡中心淋巴瘤,包括原发性皮肤滤泡中心淋巴瘤(PCFCL),罕见地可表现为浆细胞分化。这类病例可能会带来诊断上的挑战,易被误诊为更常见包含浆细胞的其他淋巴瘤。在此,我们报告了 4 例 PCFCL 和 1 例累及皮肤的系统性滤泡淋巴瘤伴单克隆浆细胞,包括临床、形态学和免疫表型特征。