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与口腔功能相关的口腔健康因素与日本老年人的死亡率相关。

Association of oral health factors related to oral function with mortality in older Japanese.

机构信息

Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi Gakuin University, Nagoya, Japan.

Mie Dental Association, Tsu, Japan.

出版信息

Gerodontology. 2021 Jun;38(2):166-173. doi: 10.1111/ger.12508. Epub 2020 Nov 12.

Abstract

OBJECTIVE

To examine the effects of oral health factors related to oral function and their combination on mortality in older people.

BACKGROUND

Recent studies have reported that oral factors, including oral function, are associated with mortality.

MATERIALS AND METHODS

The participants were 4765 community-dwelling individuals aged 75 and 80 years. The follow-up period for survival or death was 3.5 years, and the date of death was defined based on data managed by the insurer. A Cox proportional hazard model was applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality as dependent variables for oral health factors, including the number of teeth, swallowing disability, oral dryness and oral hygiene and the combinations of oral health factors as independent variables.

RESULTS

In univariate analyses, all four oral health factors were significantly associated with mortality. After adjusting for age, sex, smoking, body mass index and medical history, and analysing the oral health factors separately, swallowing difficulty had the highest HR for mortality (adjusted HR, 2.12; 95% CI, 1.35-3.33). In the analysis using combinations of oral health factors as the independent variable, the participants with swallowing disability, oral dryness and poor oral hygiene had the highest HR for mortality (adjusted HR, 8.35; 95% CI, 3.45-21.08).

CONCLUSION

Oral health factors related to oral function appear to be associated with mortality risk and an accumulation of oral health factors increases mortality risk among older people.

摘要

目的

探讨与口腔功能相关的口腔健康因素及其组合对老年人死亡率的影响。

背景

最近的研究报告称,口腔因素(包括口腔功能)与死亡率有关。

材料与方法

参与者为 4765 名 75 岁和 80 岁的社区居民。生存或死亡的随访期为 3.5 年,死亡日期根据保险公司管理的数据确定。应用 Cox 比例风险模型来估计作为依赖变量的口腔健康因素(包括牙齿数量、吞咽障碍、口腔干燥和口腔卫生)以及口腔健康因素组合的风险比(HR)和 95%置信区间(CI),用于死亡率。

结果

在单因素分析中,所有四项口腔健康因素均与死亡率显著相关。在调整年龄、性别、吸烟、体重指数和病史,并分别分析口腔健康因素后,吞咽困难对死亡率的 HR 最高(调整后的 HR,2.12;95%CI,1.35-3.33)。在使用口腔健康因素组合作为自变量的分析中,有吞咽困难、口腔干燥和口腔卫生差的参与者的死亡率 HR 最高(调整后的 HR,8.35;95%CI,3.45-21.08)。

结论

与口腔功能相关的口腔健康因素似乎与死亡率风险相关,口腔健康因素的积累增加了老年人的死亡率风险。

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