Department of Surgical Oncology, Faculty of Medicine, Comenius University and St. Elisabeth Cancer Institute, Bratislava, Slovakia.
Department of Pathology, Faculty of Medicine, Comenius University and St. Elisabeth Cancer Institute, Bratislava, Slovakia.
Neuro Endocrinol Lett. 2020 Sep;41(2):60-68.
Despite the increased incidence of pancreatic cancer, reported data of collision pancreatic tumors are very rare, limited just to sporadic cases. There are only two described cases of the collision pancreatic tumor consisting of neuroendocrine and pancreatic ductal adenocarcinoma in the literature. Currently, we are presenting a case of a young female patient with pancreatic ductal adenocarcinoma surrounding a smaller focal lesion of the well-differentiated neuroendocrine pancreatic tumor. The patient underwent proximal pancreaticoduodenectomy with uneventful postoperative course. Histogenesis of these colliding tumors remains unclear. However, there are several proposed theories. Surgical resection could be the treatment of choice of resectable cases; however, preoperative diagnosis is virtually impossible.
尽管胰腺癌的发病率有所增加,但报道的碰撞性胰腺肿瘤数据非常罕见,仅限于散发病例。文献中仅有两例描述的碰撞性胰腺肿瘤由神经内分泌和胰腺导管腺癌组成。目前,我们报告了一例年轻女性患者,其胰腺导管腺癌周围环绕着一个分化良好的神经内分泌胰腺肿瘤的较小局灶性病变。该患者行胰十二指肠近端切除术,术后无并发症。这些碰撞性肿瘤的发生机制尚不清楚。然而,有几种提出的理论。手术切除可能是可切除病例的治疗选择;然而,术前诊断几乎是不可能的。