Department of Psychiatry, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
JBI Evid Synth. 2021 Jan;19(1):201-207. doi: 10.11124/JBISRIR-D-19-00364.
The objective of this review is to evaluate the best available evidence to determine the prevalence of depression in the general population of Latin America and the Caribbean countries.
Depression is a common mental disorder that affects quality of life and has been ranked as the largest contributor to non-fatal health loss. Knowledge of this disorder serves as a relevant instrument for policy makers and for the reassignment of public health resources. Although the prevalence of depression is well documented in high-income countries, little is known about the prevalence in Latin America and the Caribbean.
This review will include studies that report the prevalence of depression in the general adult (14 years and older) population of countries in Latin America and the Caribbean. Non-representative subsets of the population will be excluded.
The search strategy will be designed to obtain both published and unpublished studies. Information sources include PubMed, PsycINFO, Cochrane CENTRAL, and SciELO. Sources of unpublished studies include literature from government departments, international agencies, and academic institution repositories or websites. Eligible studies will be critically appraised for methodological quality. Prevalence estimates will be statistically pooled in a meta-analysis after heterogeneity interpretation; data not appropriate for pooling will be reported in a narrative review. Finally, risk of publication bias will be studied via funnel plot analysis and the Egger test.
PROSPERO (CRD42019143054).
本次综述旨在评估现有最佳证据，以确定拉丁美洲和加勒比国家普通人群中抑郁症的患病率。
抑郁症是一种常见的精神障碍，它会降低生活质量，并且被列为非致命性健康损失的最大原因之一。了解这种疾病对于政策制定者和重新分配公共卫生资源具有重要意义。尽管高收入国家的抑郁症患病率已有充分记录，但对拉丁美洲和加勒比地区的患病率却知之甚少。
本次综述将纳入报告拉丁美洲和加勒比国家普通成年（14 岁及以上）人群中抑郁症患病率的研究。不包括代表性不足的人群亚组。
检索策略旨在获取已发表和未发表的研究。信息来源包括 PubMed、PsycINFO、Cochrane CENTRAL 和 SciELO。未发表研究的来源包括政府部门、国际机构以及学术机构知识库或网站的文献。将对合格研究进行方法学质量的批判性评估。在解释异质性后，将对患病率估计值进行统计汇总进行荟萃分析；不适合汇总的数据将以叙述性综述的形式报告。最后，将通过漏斗图分析和 Egger 检验研究发表偏倚的风险。
PROSPERO（CRD42019143054）。
