Lange Shannon, Probst Charlotte, Heer Navrose, Roerecke Michael, Rehm Jürgen, Monteiro Maristela G, Shield Kevin, de Oliveira Claire, Popova Svetlana
Institute for Mental Health Policy Research, Center for Addiction and Mental Health, Toronto, Ontario, Canada.
Pan American Health Organization, Washington DC, United States of America.
Rev Panam Salud Publica. 2017 Jun 8;41:e89. doi: 10.26633/RPSP.2017.89.
To estimate the prevalence of alcohol consumption during pregnancy among the general population of Latin America and the Caribbean, by country, in 2012.
Three steps were taken: a comprehensive, systematic literature search; meta-analyses, assuming a random-effects model for countries with published studies; and regression modelling (data prediction) for countries with either no published studies or too few to obtain an estimate.
Based on 24 existing studies, the pooled prevalence of alcohol consumption during pregnancy among the general population was estimated for Brazil (15.2%; 95% confidence interval [95%CI]: 10.4%-20.8%) and Mexico (1.2%; 95%CI: 0.0%-2.7%). The prevalence of alcohol consumption during pregnancy among the general population was predicted for 31 countries and ranged from 4.8% (95%CI: 4.2%-5.4%) in Cuba to 23.3% (95%CI: 20.1%-26.5%) in Grenada.
Greater prevention efforts and measures are needed in the countries of Latin America and the Caribbean to prevent pregnant women from consuming alcohol during pregnancy and decrease the rates of Fetal Alcohol Spectrum Disorder. Additional high quality studies on the prevalence of alcohol consumption during pregnancy in Latin America and the Caribbean are also needed.
估算2012年拉丁美洲和加勒比地区普通人群中孕期饮酒的患病率,按国家划分。
采取了三个步骤:全面、系统的文献检索;对于有已发表研究的国家,采用随机效应模型进行荟萃分析;对于没有已发表研究或研究数量过少无法获得估计值的国家,进行回归建模(数据预测)。
基于24项现有研究,估算出巴西普通人群孕期饮酒的合并患病率为15.2%(95%置信区间[95%CI]:10.4%-20.8%),墨西哥为1.2%(95%CI:0.0%-2.7%)。预测了31个国家普通人群孕期饮酒的患病率,范围从古巴的4.8%(95%CI:4.2%-5.4%)到格林纳达的23.3%(95%CI:20.1%-26.5%)。
拉丁美洲和加勒比地区各国需要加大预防力度和措施,以防止孕妇在孕期饮酒并降低胎儿酒精谱系障碍的发生率。还需要对拉丁美洲和加勒比地区孕期饮酒患病率开展更多高质量研究。