Department of Emergency Medicine, Ewha Womans University, Seoul, South Korea.
PLoS One. 2020 Nov 13;15(11):e0242430. doi: 10.1371/journal.pone.0242430. eCollection 2020.
Most people are frequently exposed to chemicals and chemical products. This study provides basic information on the outcomes of acute chemical ingestion of patients aged under 19 years.
Patients aged under 19 years who had ingested chemicals and thus visited the emergency department between January 2011 and December 2016 were included in this study.
In all, 1,247 patients included (1,145 in the unintentional group and 102 in the intentional group). The mean age was 3.27±4.77 in the unintentional ingestion group and 16.49±1.94 in the intentional group. In the unintentional group, detergents were most frequently ingested (by 219 patients), followed by hypochlorite-based agents, ethanol, sodium hydroxide, acetone, silica gel, and citric acid. Cases of boric acid (odds ratio [OR] = 6.131), ethylene glycol (OR = 6.541), glacial acetic acid (OR = 7.644), other hydrocarbons (OR = 4.496), hypochlorite-based agent (OR = 2.627), nicotine (OR = 5.635), and sodium peroxocarbonate (OR = 6.783) ingestion was associated with a significantly high admission rate. In the intentional group, there were 54 cases of ingestion of hypochlorite-based agent, followed by detergent, ethylene glycol, ethanol, methanol and sodium peroxycarbonate. The significant risk factors for admission in the intentional group were ingestion of ethylene glycol (OR = 37.333) and hypochlorite-based agent (OR = 5.026). There was no mortality case.
The most commonly ingested substances were sodium hypochlorite (hypochlorite-related agent), surfactants (detergent and soap), and ethanol. The ingestion of hypochlorite or ethylene glycol was the main risk factor for admission. Intentional ingestion was higher in adolescents than in children.
大多数人经常接触化学物质和化学产品。本研究提供了 19 岁以下患者急性化学物质摄入的结果的基本信息。
本研究纳入了 2011 年 1 月至 2016 年 12 月期间因摄入化学物质而到急诊科就诊的 19 岁以下患者。
共纳入 1247 例患者(无意组 1145 例,有意组 102 例)。无意组的平均年龄为 3.27±4.77 岁,有意组为 16.49±1.94 岁。在无意组中,最常摄入的是清洁剂(219 例),其次是次氯酸盐制剂、乙醇、氢氧化钠、丙酮、硅胶和柠檬酸。硼酸(比值比[OR] = 6.131)、乙二醇(OR = 6.541)、冰醋酸(OR = 7.644)、其他碳氢化合物(OR = 4.496)、次氯酸盐制剂(OR = 2.627)、尼古丁(OR = 5.635)和过碳酸钠(OR = 6.783)摄入与较高的住院率显著相关。在有意组中,有 54 例摄入次氯酸盐制剂,其次是清洁剂、乙二醇、乙醇、甲醇和过碳酸钠。有意组中住院的显著危险因素是摄入乙二醇(OR = 37.333)和次氯酸盐制剂(OR = 5.026)。无死亡病例。
最常摄入的物质是次氯酸钠(次氯酸盐相关制剂)、表面活性剂(清洁剂和肥皂)和乙醇。摄入次氯酸盐或乙二醇是住院的主要危险因素。青少年有意摄入的比例高于儿童。