Fiore P M, Jacobs I H, Goldberg D B
Department of Ophthalmology, Eye Institute of New Jersey, Newark.
Arch Ophthalmol. 1987 Dec;105(12):1660-3. doi: 10.1001/archopht.1987.01060120058023.
Drug-induced ocular pemphigoid has been reported to occur after long-term use of topical glaucoma medications. We have reviewed the literature on drug-induced ocular pemphigoid and have added our experience with five patients with glaucoma who developed ocular cicatricial (benign mucosal) pemphigoid after treatment with various topical glaucoma medications. We also describe a case of timolol-induced ocular pemphigoid. The presentation and progression of drug-induced ocular cicatricial pemphigoid can be variable. We propose that drug-induced ocular pemphigoid represents a spectrum of diseases ranging from a self-limiting, toxic form to a progressive, immunologic form.
据报道，长期使用局部青光眼药物后会发生药物性眼类天疱疮。我们回顾了关于药物性眼类天疱疮的文献，并补充了我们对五例青光眼患者的经验，这些患者在使用各种局部青光眼药物治疗后发生了眼瘢痕性（良性黏膜）类天疱疮。我们还描述了一例噻吗洛尔诱发的眼类天疱疮病例。药物性眼瘢痕性类天疱疮的表现和进展可能各不相同。我们认为，药物性眼类天疱疮代表了一系列疾病，范围从自限性、中毒性形式到进行性、免疫性形式。
