Post-Graduate Program in Medical Sciences, School of Medicine, Universidade Federal Do Rio Grande Do Sul (UFRGS), Ramiro Barcelos, 2350, Bairro Rio, Porto Alegre, CEP 90035-003, Brazil.
Laboratory of Pain and Neuromodulation At Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Health Qual Life Outcomes. 2020 Nov 14;18(1):368. doi: 10.1186/s12955-020-01621-8.
To assess the psychometric properties, including internal consistency, construct validity, criterion validity, criterion-group validity, and responsiveness, the Reviewed McGill Quality of Life Questionnaire (MQOL-R), into Brazilian Portuguese-(BrP). Also, to analyze the relationship of the BrP-MQOL-R with the scores on the Karnofsky Performance Scale (KPS) and on the Numerical Pain Scale (NPS 0-10).
The BrP-MQOL-R was administered to a sample of 146 adults (men = 78). A team of experts translated the MQOL-R according to international guidelines. Convergent validity and Confirmatory factor analysis (CFA) was performed.
The BrP-MQOL-R Cronbach's alpha was 0.85. CFA supported the original four-factor structure, with the following revised model fit-indices: PCLOSE = 0.131, Tucker-Lewis Index (TLI) rho 2 = 0.918, incremental fit index (IFI) delta 2 = 0.936. The convergence validity is supported by a significant correlation between BrP-MQOL-R total scores and their subscales with KPS and with the single item related to the quality of life. And by a converse correlation with the pain scores in the NPS (0-10). Receiver operator characteristics (ROC) analysis showed subjects with KPS equal to or lower than 30% could be discriminated from those with scores on KPS higher than 30% by an area under the curve (AUC) = 0.71, sensitivity = 97%, and specificity = 92%).
The BrP-MQOL-R proves to be a reliable instrument for assessing the quality of life (QOL) in palliative care (PC), with primary evidence of validity. BrP-MQOL-R presented adequate discriminate properties to identify distinct conditions that impact the QOL in PC.
为了评估心理计量特性，包括内部一致性、结构效度、效标效度、效标组效度和反应度，对修订后的麦吉尔生活质量问卷（MQOL-R）进行了巴西葡萄牙语-（BrP）翻译。还分析了 BrP-MQOL-R 与卡诺夫斯基绩效量表（KPS）和数字疼痛量表（NPS 0-10）得分的关系。
BrP-MQOL-R 对 146 名成年人（男性=78 名）进行了测试。一个专家组按照国际指南对 MQOL-R 进行了翻译。进行了收敛效度和验证性因素分析（CFA）。
BrP-MQOL-R 的 Cronbach's alpha 为 0.85。CFA 支持了最初的四因素结构，以下是修正模型拟合指数：接近概率（PCLOSE）=0.131，Tucker-Lewis 指数（TLI）rho 2=0.918，增量拟合指数（IFI）delta 2=0.936。BrP-MQOL-R 总分与其子量表与 KPS 和与生活质量相关的单一项目之间的显著相关性支持了收敛效度。与 NPS（0-10）中的疼痛评分呈反向相关性。接受者操作特征（ROC）分析表明，KPS 等于或低于 30%的患者可以通过曲线下面积（AUC）=0.71、灵敏度=97%和特异性=92%与 KPS 高于 30%的患者区分开来。
BrP-MQOL-R 是评估姑息治疗（PC）生活质量（QOL）的可靠工具，具有初步的有效性证据。BrP-MQOL-R 具有足够的判别特性，可以识别影响 PC 中 QOL 的不同情况。
