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麦吉尔生活质量问卷修订版(MQOL-R)。对巴西姑息治疗患者的心理测量特性和验证:一项横断面研究。

The McGill Quality of Life Questionnaire-Revised (MQOL-R). Psychometric properties and validation of a Brazilian version on palliative care patients: a cross-sectional study.

机构信息

Post-Graduate Program in Medical Sciences, School of Medicine, Universidade Federal Do Rio Grande Do Sul (UFRGS), Ramiro Barcelos, 2350, Bairro Rio, Porto Alegre, CEP 90035-003, Brazil.

Laboratory of Pain and Neuromodulation At Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.

出版信息

Health Qual Life Outcomes. 2020 Nov 14;18(1):368. doi: 10.1186/s12955-020-01621-8.

Abstract

BACKGROUND

To assess the psychometric properties, including internal consistency, construct validity, criterion validity, criterion-group validity, and responsiveness, the Reviewed McGill Quality of Life Questionnaire (MQOL-R), into Brazilian Portuguese-(BrP). Also, to analyze the relationship of the BrP-MQOL-R with the scores on the Karnofsky Performance Scale (KPS) and on the Numerical Pain Scale (NPS 0-10).

METHODS

The BrP-MQOL-R was administered to a sample of 146 adults (men = 78). A team of experts translated the MQOL-R according to international guidelines. Convergent validity and Confirmatory factor analysis (CFA) was performed.

RESULTS

The BrP-MQOL-R Cronbach's alpha was 0.85. CFA supported the original four-factor structure, with the following revised model fit-indices: PCLOSE = 0.131, Tucker-Lewis Index (TLI) rho 2 = 0.918, incremental fit index (IFI) delta 2 = 0.936. The convergence validity is supported by a significant correlation between BrP-MQOL-R total scores and their subscales with KPS and with the single item related to the quality of life. And by a converse correlation with the pain scores in the NPS (0-10). Receiver operator characteristics (ROC) analysis showed subjects with KPS equal to or lower than 30% could be discriminated from those with scores on KPS higher than 30% by an area under the curve (AUC) = 0.71, sensitivity = 97%, and specificity = 92%).

CONCLUSION

The BrP-MQOL-R proves to be a reliable instrument for assessing the quality of life (QOL) in palliative care (PC), with primary evidence of validity. BrP-MQOL-R presented adequate discriminate properties to identify distinct conditions that impact the QOL in PC.

摘要

背景

为了评估心理计量特性,包括内部一致性、结构效度、效标效度、效标组效度和反应度,对修订后的麦吉尔生活质量问卷(MQOL-R)进行了巴西葡萄牙语-(BrP)翻译。还分析了 BrP-MQOL-R 与卡诺夫斯基绩效量表(KPS)和数字疼痛量表(NPS 0-10)得分的关系。

方法

BrP-MQOL-R 对 146 名成年人(男性=78 名)进行了测试。一个专家组按照国际指南对 MQOL-R 进行了翻译。进行了收敛效度和验证性因素分析(CFA)。

结果

BrP-MQOL-R 的 Cronbach's alpha 为 0.85。CFA 支持了最初的四因素结构,以下是修正模型拟合指数:接近概率(PCLOSE)=0.131,Tucker-Lewis 指数(TLI)rho 2=0.918,增量拟合指数(IFI)delta 2=0.936。BrP-MQOL-R 总分与其子量表与 KPS 和与生活质量相关的单一项目之间的显著相关性支持了收敛效度。与 NPS(0-10)中的疼痛评分呈反向相关性。接受者操作特征(ROC)分析表明,KPS 等于或低于 30%的患者可以通过曲线下面积(AUC)=0.71、灵敏度=97%和特异性=92%与 KPS 高于 30%的患者区分开来。

结论

BrP-MQOL-R 是评估姑息治疗(PC)生活质量(QOL)的可靠工具,具有初步的有效性证据。BrP-MQOL-R 具有足够的判别特性,可以识别影响 PC 中 QOL 的不同情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9705/7666518/8e9e269f145a/12955_2020_1621_Fig1_HTML.jpg

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