Menz P, Jackson I T, Connolly S
Section of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester.
Br J Plast Surg. 1987 Nov;40(6):557-61. doi: 10.1016/0007-1226(87)90148-2.
Hailey-Hailey disease is a benign, chronic genodermatosis manifested by recurrent lesions with a predilection for the intertriginous areas. The malodorous, weeping sores are a source of great discomfort to the patient. Medical therapy controls most lesions adequately; however, some are refractory. Experience with excision of skin involved with Hailey-Hailey disease is reported. The best results were obtained in those patients whose wounds were resurfaced with split skin grafts. Primary suture was associated with recurrent disease and residual morbidity. The findings of other isolated reports in the literature are also summarised. The results show that surgical control of Hailey-Hailey disease is indicated in recalcitrant cases.
黑利-黑利病是一种良性慢性遗传性皮肤病，表现为反复发作的皮损，好发于皮肤褶皱部位。恶臭、渗液的溃疡给患者带来极大不适。药物治疗能充分控制大多数皮损；然而，有些皮损难以治愈。本文报告了切除黑利-黑利病累及皮肤的经验。采用中厚皮片移植覆盖创面的患者取得了最佳效果。一期缝合与疾病复发及残留并发症相关。本文还总结了文献中其他个别报告的研究结果。结果表明，对于顽固病例，手术治疗黑利-黑利病是可行的。
