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起搏器附近剂量计算的准确性:一项针对三种商用治疗计划系统的多中心研究。

Dose calculation accuracy in proximity of a pacemaker: A multicenter study with threecommercial treatment planning systems.

作者信息

Delana Anna, Barbareschi Agnese, Consorti Rita, Daniela Falco Maria

机构信息

Department of Medical Physics, S.Chiara Hospital, APSS Trento, Italy.

Department of Medical Physics, ASST Spedali Civili di Brescia, Brescia, Italy.

出版信息

Phys Med. 2020 Dec;80:201-208. doi: 10.1016/j.ejmp.2020.10.015. Epub 2020 Nov 12.

Abstract

This study compares Treatment Planning System (TPS) out of field dose calculation on a pacemaker (PMK) during external beam radiotherapy treatment. We consider four TPSs (Elekta-Monaco, Oncentra- Masterplan and two Philips-Pinnacle3) commissioned for two linacs (Elekta Sinergy and Varian Clinac) delivering two test beams (a highly modulated one and a square field) and two clinical breast plans. To calculate and measure dose to a PMK we built a Real Water3 phantom with a PMK embedded in it. Measures are performed with thermo-luminescent dosimeters and Mosfet dosimeters. We evaluate differences between TPS calculated values for the dose to the PMK (both point dose and dose-volume histogram parameters) when the PMK is positioned in the first 10 cm outside the radiation fields. TPS calculation accuracy is evaluated comparing such values with measures. Differences in TPS calculations are on average 3.5 cGy Gy for the modulated beam, and always lower than 2 cGy Gy for the square beam. TPS dose calculation depends mostly on the TPS algorithm and model rather than the linac commissioned. TPSs considered show different degrees of calculation accuracy. In the first 4 cm to the field edge three out of four TPSs are in good agreement with measurements in the square beam, but only one keeps the agreement in the modulated beam: the others show over and underestimations up to +20% -40%. The same accuracy is found considering a homogeneous phantom. Our results confirm what reported in previous studies and highlight the impact of TPS commissioning.

摘要

本研究比较了在体外放射治疗期间,治疗计划系统(TPS)对起搏器(PMK)的射野外剂量计算。我们考虑了针对两台直线加速器(医科达Synergy和瓦里安Clinac)调试的四种TPS(医科达-Monaco、Oncentra-Masterplan和两种飞利浦-Pinnacle3),这两台直线加速器可提供两种测试射束(一种高度调制射束和一个方野)以及两种临床乳腺计划。为了计算和测量PMK的剂量,我们构建了一个嵌入PMK的Real Water3模体。使用热释光剂量计和Mosfet剂量计进行测量。当PMK位于辐射野之外的前10厘米时,我们评估TPS计算的PMK剂量值(点剂量和剂量体积直方图参数)之间的差异。通过将这些值与测量值进行比较来评估TPS计算的准确性。对于调制射束,TPS计算差异平均为3.5 cGy/Gy,对于方野射束则始终低于2 cGy/Gy。TPS剂量计算主要取决于TPS算法和模型,而非调试的直线加速器。所考虑的TPS显示出不同程度的计算准确性。在距射野边缘的前4厘米处,四分之三的TPS在方野射束中与测量值吻合良好,但在调制射束中只有一种保持吻合:其他的显示出高达+20% -40%的高估和低估。考虑均匀模体时也发现了相同的准确性。我们的结果证实了先前研究中所报道的内容,并突出了TPS调试的影响。

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