Sagar S M
Neurology Service, Veterans Administration Medical Center, San Francisco, CA 94143.
Brain Res. 1987 Nov 17;426(1):157-63. doi: 10.1016/0006-8993(87)90435-5.
A commercially obtained antiserum to vasoactive intestinal polypeptide (VIP) was used with the avidin-biotin-peroxidase immunohistochemical method to localize VIP-like immunoreactivity in the adult rabbit retina. A population of cell bodies in the inner nuclear layer is specifically stained. The cells are most dense in the central retina (40-50 cells/mm2), and least numerous in the superior periphery (15-20 cells/mm2). The dendritic fields overlap extensively; cells in the periphery have dendritic fields up to 1 mm in diameter. The processes of the cells are in the inner plexiform layer, where they tend to form a tristratified pattern in sublayers 1, 3 and 5. This pattern of lamination is similar to that described by other laboratories for dopaminergic amacrine cells and provides further evidence for an interaction between these two neuromodulators.
使用市售的抗血管活性肠肽（VIP）抗血清，采用抗生物素蛋白-生物素-过氧化物酶免疫组织化学方法，在成年兔视网膜中定位VIP样免疫反应性。内核层中的一群细胞体被特异性染色。这些细胞在视网膜中央最为密集（40 - 50个细胞/mm²），在上周边部数量最少（15 - 20个细胞/mm²）。树突野广泛重叠；周边部的细胞树突野直径可达1毫米。这些细胞的突起位于内网层，在第1、3和5亚层倾向于形成三层结构模式。这种分层模式与其他实验室描述的多巴胺能无长突细胞的模式相似，并为这两种神经调质之间的相互作用提供了进一步的证据。
