Falkoff R
Department of Allergy-Immunology, Kaiser Permanente Medical Center, San Diego, California 92111.
Clin Rev Allergy. 1987 Nov;5(4):287-300.
A great variety of approaches have been applied to the study of immunity during pregnancy. Many of the studies have been motivated by an attempt to explain the failure of of the mother to reject the fetus. At times, dramatic findings have been claimed; and, at times, these results have been held to be expected, since no immunologic event (or nonevent) has been more perplexing than the failure of the mother to reject the fetal "allograft." This review will present clinical findings relevant to an understanding of immunocompetence and host defense during pregnancy, as well as the results of laboratory investigations regarding the possibility of altered immunity during pregnancy.
人们运用了各种各样的方法来研究孕期免疫。许多研究的动机是试图解释母亲为何不会排斥胎儿。有时，会宣称有惊人的发现；而有时，这些结果又被认为是意料之中的，因为没有哪种免疫事件（或非事件）比母亲未能排斥胎儿“同种异体移植物”更令人困惑了。本综述将呈现与理解孕期免疫能力和宿主防御相关的临床发现，以及关于孕期免疫可能发生改变的实验室研究结果。
