Effectiveness of Fiber Supplementation for Constipation, Weight Loss, and Supporting Gastrointestinal Function: A Narrative Review of Meta-Analyses.

OBJECTIVE

The purpose of this narrative review is to determine whether published meta-analyses support the use of fiber supplementation in the treatment of constipation, weight loss, and dietary support for gastrointestinal disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease.

METHODS

A PubMed search from January 1, 1980, to July 31, 2019, was conducted with the following search strategy: (fiber OR fibre) AND (meta-analysis OR systematic review) AND (constipation OR body weight OR obesity OR irritable bowel syndrome OR inflammatory bowel disease). Meta-analyses that provided quantitative statistical analysis with a measured effect size were retrieved and accepted into this review. The following was extracted and entered into an Excel spreadsheet: number of publications included in the meta-analysis, number of total participants, fiber type and daily dose, pooled treatment effects for clinical endpoints, or summary relative risks.

RESULTS

Eighteen meta-analyses support dietary fiber supplementation for patients with constipation, weight loss, and IBS, but the significant heterogeneity and publication bias undermine the support for using dietary fiber supplementation in these conditions.

CONCLUSION

This narrative review of meta-analyses finds some benefits for recommending fiber supplementation to patients with constipation, obesity, and IBS, but significant heterogeneity and publication bias undermine this support.